Possible interactions between leukemic and stromal cells.
| Adapted from Dührsen and Hossfeld.11 |
| • Promotion of leukemic cell growth |
| Inhibition of apoptosis |
| Blockade of differentiation |
| Stimulation of proliferation |
| Growth stimulation by hepatocyte growth factors (HGFs) |
| • Inhibition of leukemic cell growth |
| Induction of differentiation |
| Inhibition of proliferation |
| • Inhibition of stromal cell growth |
| Adapted from Dührsen and Hossfeld.11 |
| • Promotion of leukemic cell growth |
| Inhibition of apoptosis |
| Blockade of differentiation |
| Stimulation of proliferation |
| Growth stimulation by hepatocyte growth factors (HGFs) |
| • Inhibition of leukemic cell growth |
| Induction of differentiation |
| Inhibition of proliferation |
| • Inhibition of stromal cell growth |