Table 8.

Changes of the von Willebrand factor cleaving protease activity in various clinical conditions.

N denotes normal levels 
TTP  
    Acute sporadic or chronic relapsing ↓↓↓↓ AGING ↓ 
    Transplantation-associated N NEWBORNS ↓↓↓ 
    Ticlopidine- or Clopidogrel-associated ↓↓↓ PREGNANCY ↓↓ 
    Cancer-associated ↓↓↓ CIRRHOSIS ↓↓↓ 
HUS UREMIA ↓↓ 
    Acute sporadic N ↓↓↓ INFLAMMATION 
    Chronic relapsing ↓↓↓↓ POST-OPERATIVE PERIOD ↓↓↓ 
N denotes normal levels 
TTP  
    Acute sporadic or chronic relapsing ↓↓↓↓ AGING ↓ 
    Transplantation-associated N NEWBORNS ↓↓↓ 
    Ticlopidine- or Clopidogrel-associated ↓↓↓ PREGNANCY ↓↓ 
    Cancer-associated ↓↓↓ CIRRHOSIS ↓↓↓ 
HUS UREMIA ↓↓ 
    Acute sporadic N ↓↓↓ INFLAMMATION 
    Chronic relapsing ↓↓↓↓ POST-OPERATIVE PERIOD ↓↓↓