Treatments of refractory immune thrombocytopenic purpura.
Abbreviations: CHOP, cyclophosphamide, adriamycin, vincristine, prednisone; VCR-IVIG-SM, VCR; intravenous gammaglobulin; SM, Solumedrol |
I. Promising treatments: |
a. combination chemotherapy: CHOP-like, VCR-IVIG-SM (Table 6) |
b. anti-CD40 Ligand |
c. rituximab |
d. ? thrombopoietin or thrombopoietin like substances |
e. autologous bone marrow transplantation |
II. Treatments that have an apparent low likelihood of success when used alone in refractory patients: |
a. Interleukin-11 (Neumega) |
b. Anti-D |
c. Interferon |
d. Staph protein A columns |
e. Plasmapheresis |
Abbreviations: CHOP, cyclophosphamide, adriamycin, vincristine, prednisone; VCR-IVIG-SM, VCR; intravenous gammaglobulin; SM, Solumedrol |
I. Promising treatments: |
a. combination chemotherapy: CHOP-like, VCR-IVIG-SM (Table 6) |
b. anti-CD40 Ligand |
c. rituximab |
d. ? thrombopoietin or thrombopoietin like substances |
e. autologous bone marrow transplantation |
II. Treatments that have an apparent low likelihood of success when used alone in refractory patients: |
a. Interleukin-11 (Neumega) |
b. Anti-D |
c. Interferon |
d. Staph protein A columns |
e. Plasmapheresis |