Differentiation of pregnancy-associated microangiopathies.*
| . | MAHA . | Thrombo-cytopenia . | Coagulo-pathy . | Hyper-tension . | Renal Disease . | CNS Disease . | Time of Onset . |
|---|---|---|---|---|---|---|---|
| Abbreviations: MAHA, microangiopathic hemolytic anemia; CNS, central nervous system; HELLP, hemolysis, elevated liver function tests, low platelets syndrome: HUS, hemolytic uremic syndrome: TTP, thrombotic thrombocytopenic purpura; SLE, systemic lupus erythematosus; APS, antiphospholipid syndrome; AFLP, acute fatty liver of pregnancy; ±, variably present; +, mild; ++, moderate; +++, severe | |||||||
| * Modified from McCrae and Cines, Semin Hematol. 1997;34:148 (reference 4) | |||||||
| Preeclampsia | + | + | ± | +++ | + | + | 3rd trimester |
| HELLP | ++ | +++ | + | ± | + | ± | 3rd trimester |
| HUS | ++ | ++ | ± | ± | +++ | ± | Postpartum |
| TTP | +++ | +++ | ± | ± | +/± | +++ | 2nd trimester |
| SLE | ± to +++ | + | ± | ± | +/++ | + | Anytime |
| APS | - to ± | + | ± | ± | ± | + | Anytime |
| AFLP | + | +/± | +++ | ± | ± | + | 3rd trimester |
| . | MAHA . | Thrombo-cytopenia . | Coagulo-pathy . | Hyper-tension . | Renal Disease . | CNS Disease . | Time of Onset . |
|---|---|---|---|---|---|---|---|
| Abbreviations: MAHA, microangiopathic hemolytic anemia; CNS, central nervous system; HELLP, hemolysis, elevated liver function tests, low platelets syndrome: HUS, hemolytic uremic syndrome: TTP, thrombotic thrombocytopenic purpura; SLE, systemic lupus erythematosus; APS, antiphospholipid syndrome; AFLP, acute fatty liver of pregnancy; ±, variably present; +, mild; ++, moderate; +++, severe | |||||||
| * Modified from McCrae and Cines, Semin Hematol. 1997;34:148 (reference 4) | |||||||
| Preeclampsia | + | + | ± | +++ | + | + | 3rd trimester |
| HELLP | ++ | +++ | + | ± | + | ± | 3rd trimester |
| HUS | ++ | ++ | ± | ± | +++ | ± | Postpartum |
| TTP | +++ | +++ | ± | ± | +/± | +++ | 2nd trimester |
| SLE | ± to +++ | + | ± | ± | +/++ | + | Anytime |
| APS | - to ± | + | ± | ± | ± | + | Anytime |
| AFLP | + | +/± | +++ | ± | ± | + | 3rd trimester |