Table 5.

Summary of major recommendations for prevention of herpes simplex virus (HSV).

Type of PreventionRating
Prevention of Exposure  
Testing of recipient IgG serostatus AIII 
Counseling of seronegative recipient on transmission mode of HSV AII 
Use of latex condoms during sexual contacts in sexually active seronegative recipients not in long-term monogamous relationships AII 
Counseling of seronegative recipient of behavior that will decrease HSV transmission AII 
Contact isolation for persons with disseminated, severe, or severe mucocutaneous HSV disease AI 
Prevention of Disease or Disease Recurrence  
Acyclovir prophylaxis in seropositive allograft recipients AI 
Duration of acyclovir prophylaxis: start of conditioning until engraftment or resolution of mucositis BII 
Type of PreventionRating
Prevention of Exposure  
Testing of recipient IgG serostatus AIII 
Counseling of seronegative recipient on transmission mode of HSV AII 
Use of latex condoms during sexual contacts in sexually active seronegative recipients not in long-term monogamous relationships AII 
Counseling of seronegative recipient of behavior that will decrease HSV transmission AII 
Contact isolation for persons with disseminated, severe, or severe mucocutaneous HSV disease AI 
Prevention of Disease or Disease Recurrence  
Acyclovir prophylaxis in seropositive allograft recipients AI 
Duration of acyclovir prophylaxis: start of conditioning until engraftment or resolution of mucositis BII 
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