Table 7.

Multivariate analysis of the association between aGVHD with 100-day and 1-year mortality




100-d mortality

1-y mortality
GVHD grade
No.
Odds ratio
P
Odds ratio
P
IBMTR      
No GVHD   157   1.00    1.00   
Maximum grade of A or B   275   0.27   < .001   0.80   .266  
Maximum grade of C   102   0.87   .644   1.42   .175  
Maximum grade of D   58   3.60   < .001   12.3   < .001  
Glucksberg      
No GVHD   157   1.00    1.00   
Maximum grade of I or II   285   0.29   < .001   0.8   .166  
Maximum grade of III   109   1.04   .900   2.2   .002  
Maximum grade of IV
 
41
 
4.30
 
< .001
 
13.1
 
< .001
 



100-d mortality

1-y mortality
GVHD grade
No.
Odds ratio
P
Odds ratio
P
IBMTR      
No GVHD   157   1.00    1.00   
Maximum grade of A or B   275   0.27   < .001   0.80   .266  
Maximum grade of C   102   0.87   .644   1.42   .175  
Maximum grade of D   58   3.60   < .001   12.3   < .001  
Glucksberg      
No GVHD   157   1.00    1.00   
Maximum grade of I or II   285   0.29   < .001   0.8   .166  
Maximum grade of III   109   1.04   .900   2.2   .002  
Maximum grade of IV
 
41
 
4.30
 
< .001
 
13.1
 
< .001
 

Neither time of onset or number of episodes of aGVHD were significant in these models, once maximum grade was entered.

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