Table 5.

Cross-reactivity of NKp80 (Ma152 mAb, Lapi mAb, Cer1 mAb) on human and simian lymphocytes



Mean (range), %
Donors
CD3neg/HLA-DRnegNKp80pos
CD3neg/HLA-DRnegNKp80neg
CD3pos/HLA-DRposNKp80pos
Human, n = 13   96.7 (95-98)   2.3 (2-5)   29 (7-42)  
Rhesus, n = 17   97.5 (97-99)   2.5 (1-3)   21 (7-36)  
Pigtailed, n = 10
 
97.8 (97-99)
 
2.2 (1-3)
 
24 (8-37)
 


Mean (range), %
Donors
CD3neg/HLA-DRnegNKp80pos
CD3neg/HLA-DRnegNKp80neg
CD3pos/HLA-DRposNKp80pos
Human, n = 13   96.7 (95-98)   2.3 (2-5)   29 (7-42)  
Rhesus, n = 17   97.5 (97-99)   2.5 (1-3)   21 (7-36)  
Pigtailed, n = 10
 
97.8 (97-99)
 
2.2 (1-3)
 
24 (8-37)
 

The anti-human NKp80 mAbs Ma152, Lapi, and Cer1 cross-reacted with the same affinity with human and simian lymphocytes.

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