Characteristics of erythrocytes and reticulocytes in 4.1-/- mice and controls
. | 4.1-/- . | C57BL6 . | 129S1/SvImj . |
|---|---|---|---|
| No. experiments | 15 | 12 | 12 |
| Erythrocytes | |||
| MCV, fL | 43.1 ± 1.6* | 49.3 ± 0.9 | 50.3 ± 0.7 |
| RDW, % | 25.3 ± 2.1* | 13.2 ± 0.9 | 12.9 ± 0.4 |
| CHCM, g/dL | 32.7 ± 0.9* | 28.5 ± 0.6 | 29.7 ± 0.6 |
| HDW, g/dL | 3.46 ± 0.38* | 1.9 ± 0.01 | 1.85 ± 0.1 |
| D50 | 1.111 ± 0.001 | 1.096 ± 0.002 | — |
| Cell Na, mmol/kg Hb | 48.5 ± 8.8* | 13.0 ± 2.0 | 12.8 ± 5.0 |
| Cell K, mmol/kg Hb | 343.9 ± 36.4* | 444.2 ± 14.4 | 446.5 ± 12.7 |
| Cell Na + K, mmol/kg Hb | 392.3 ± 38.4* | 457.2 ± 16.3 | 459.3 ± 13.5 |
| Reticulocytes | |||
| Reticulocytes, % | 20.7 ± 2.7* | 3.3 ± 0.6 | 2.7 ± 0.7 |
| MCVr, fL | 55.3 ± 1.4 | 57.5 ± 1.3 | 57.5 ± 2.4 |
| RDWr, % | 17.8 ± 1.4 | 14.9 ± 1.5 | 15.5 ± 2.0 |
| CHCMr, g/dL | 28.1 ± 0.4 | 28.0 ± 0.7 | 29.0 ± 0.9 |
| HDWr, g/dL | 2.8 ± 0.17 | 2.9 ± 0.4 | 2.8 ± 0.3 |
. | 4.1-/- . | C57BL6 . | 129S1/SvImj . |
|---|---|---|---|
| No. experiments | 15 | 12 | 12 |
| Erythrocytes | |||
| MCV, fL | 43.1 ± 1.6* | 49.3 ± 0.9 | 50.3 ± 0.7 |
| RDW, % | 25.3 ± 2.1* | 13.2 ± 0.9 | 12.9 ± 0.4 |
| CHCM, g/dL | 32.7 ± 0.9* | 28.5 ± 0.6 | 29.7 ± 0.6 |
| HDW, g/dL | 3.46 ± 0.38* | 1.9 ± 0.01 | 1.85 ± 0.1 |
| D50 | 1.111 ± 0.001 | 1.096 ± 0.002 | — |
| Cell Na, mmol/kg Hb | 48.5 ± 8.8* | 13.0 ± 2.0 | 12.8 ± 5.0 |
| Cell K, mmol/kg Hb | 343.9 ± 36.4* | 444.2 ± 14.4 | 446.5 ± 12.7 |
| Cell Na + K, mmol/kg Hb | 392.3 ± 38.4* | 457.2 ± 16.3 | 459.3 ± 13.5 |
| Reticulocytes | |||
| Reticulocytes, % | 20.7 ± 2.7* | 3.3 ± 0.6 | 2.7 ± 0.7 |
| MCVr, fL | 55.3 ± 1.4 | 57.5 ± 1.3 | 57.5 ± 2.4 |
| RDWr, % | 17.8 ± 1.4 | 14.9 ± 1.5 | 15.5 ± 2.0 |
| CHCMr, g/dL | 28.1 ± 0.4 | 28.0 ± 0.7 | 29.0 ± 0.9 |
| HDWr, g/dL | 2.8 ± 0.17 | 2.9 ± 0.4 | 2.8 ± 0.3 |
Data are presented as mean ± SD.
— indicates not determined.
P < .05 compared with C57BL6 and 129S1/SvImj.