Currently active National Cancer Institute (NCI)-sponsored clinical trials with rituximab.
| SWOG E4494/ECOG E4494/CALGB 9793 | Phase III trial of CHOP vs. CHOP and rituximab in older patients with diffuse mixed, diffuse large cell, and immunoblastic large cell histology non-Hodgkin's lymphoma. |
| CALGB 9712 | A randomized phase II study of concurrent fludarabine plus rituximab induction followed by rituximab consolidation vs. fludarabine induction followed by rituximab consolidation in untreated patients with B cell chronic lymphocytic leukemia. |
| AMC 010 | Randomized trial of CHOP chemotherapy with or without rituximab for HIV associated non-Hodgkin's lymphoma |
| ECOG T96-0075 | Phase II study of CHOP and rituximab in patients with mantle cell lymphoma |
| ECOG E1496 | Randomized phase II study in low grade lymphoma comparing Standard CVP chemotherapy with or without rituximab maintenance |
| Abbreviations: SWOG, Southwest Oncology Group; CALGB, Cancer and Acute Leukemia Group B; ECOG, Eastern Cooperative Oncology Group | |
| SWOG E4494/ECOG E4494/CALGB 9793 | Phase III trial of CHOP vs. CHOP and rituximab in older patients with diffuse mixed, diffuse large cell, and immunoblastic large cell histology non-Hodgkin's lymphoma. |
| CALGB 9712 | A randomized phase II study of concurrent fludarabine plus rituximab induction followed by rituximab consolidation vs. fludarabine induction followed by rituximab consolidation in untreated patients with B cell chronic lymphocytic leukemia. |
| AMC 010 | Randomized trial of CHOP chemotherapy with or without rituximab for HIV associated non-Hodgkin's lymphoma |
| ECOG T96-0075 | Phase II study of CHOP and rituximab in patients with mantle cell lymphoma |
| ECOG E1496 | Randomized phase II study in low grade lymphoma comparing Standard CVP chemotherapy with or without rituximab maintenance |
| Abbreviations: SWOG, Southwest Oncology Group; CALGB, Cancer and Acute Leukemia Group B; ECOG, Eastern Cooperative Oncology Group | |