Clinical outcomes with usual care versus anticoagulation clinic care.
| Studies . | Patient Years . | Major Hemorrhage . | Thromboembolism . | Combined . |
|---|---|---|---|---|
| . | (%/pt yr) . | (%/pt yr) . | (%/pt yr) . | . |
| Usual care studies* | 1,537 | 6.8% | 8.1% | ∼ 15% |
| Anticoagulation clinic studies** | 19,361 | 4.3% | 4.8% | ∼ 9% |
| Comparison studies: | ||||
| Usual care | 944 | 5.7% | 8.4% | ∼ 14% |
| vs | ||||
| Anticoagulation clinic# | 986 | 1.6% | 1.5% | ∼ 3% |
| Studies . | Patient Years . | Major Hemorrhage . | Thromboembolism . | Combined . |
|---|---|---|---|---|
| . | (%/pt yr) . | (%/pt yr) . | (%/pt yr) . | . |
| Usual care studies* | 1,537 | 6.8% | 8.1% | ∼ 15% |
| Anticoagulation clinic studies** | 19,361 | 4.3% | 4.8% | ∼ 9% |
| Comparison studies: | ||||
| Usual care | 944 | 5.7% | 8.4% | ∼ 14% |
| vs | ||||
| Anticoagulation clinic# | 986 | 1.6% | 1.5% | ∼ 3% |
Landefeld 1989, 106 Gitter 1995, 116 Beyth 1998. 112
Davis 1977, 128 Fofar 1982, 118 Errichetti 1984, 119 Conte 1986, 145 Petty 1988, 120 Charney 1988, 121 Bussey 1989, 122 Seabrook 1990, 146 Fihn 1993, 97 van der Meer 1993, 108 Cannegieter 1995, 104 Palareti 1996 115
Garabedian 1985, 148 Cortelazzo 1993, 114 Wilt 1995, 149 Chiquette 1998; 150 these represent individual studies that assessed outcomes in both usual care and an anticoagulation clinic. They also represent a greater proportion of more recent studies utilizing the INR and low and high intensity of therapy compared to the anticoagulation clinic studies only.