NST for patients with MDS receiving matched sibling or matched unrelated donor (MUD) grafts.
Total No. . | Donors . | Conditioning . | Status (No.) . | Engraftment . | Alive & Disease-free . | Center . |
---|---|---|---|---|---|---|
8 | Sibling | Fludarabine/Bu/ATG | RAEB (3) | 3/3 | 3/3 | Jerusalem, Israel |
Second RAEB (5) | 5/5 | 2/5 | ||||
4 | Sibling | Flag/Ida or 2CDA/araC | First CR (2) | 3/4 | 2/4 | Houston, Texas, USA |
Relapse (2) | ||||||
4 | Sibling | Fludarabine/melphalan* | Relapse (4) | 4/4 | 1/4 | Houston, Texas, USA |
4 | MUD | Fludarabine/melphalan* | Relapse (4) | 4/4 | 1/4 | Houston, Texas, USA |
5 | MUD | Fludarabine/Bu/ATG | RAEB-T (3) | 3/5 | 1/5 | Dresden, Germany |
RAEB (1) | ||||||
Third PR (1) | ||||||
Abbreviations: Bu, busulfan; ATG, antithymocyte globulin; Flag/Ida, fludarabine, cytosine arabinoside, G-CSF, and idarubicin; RAEB-T, refractory anemia with excess blasts in transformation |
Total No. . | Donors . | Conditioning . | Status (No.) . | Engraftment . | Alive & Disease-free . | Center . |
---|---|---|---|---|---|---|
8 | Sibling | Fludarabine/Bu/ATG | RAEB (3) | 3/3 | 3/3 | Jerusalem, Israel |
Second RAEB (5) | 5/5 | 2/5 | ||||
4 | Sibling | Flag/Ida or 2CDA/araC | First CR (2) | 3/4 | 2/4 | Houston, Texas, USA |
Relapse (2) | ||||||
4 | Sibling | Fludarabine/melphalan* | Relapse (4) | 4/4 | 1/4 | Houston, Texas, USA |
4 | MUD | Fludarabine/melphalan* | Relapse (4) | 4/4 | 1/4 | Houston, Texas, USA |
5 | MUD | Fludarabine/Bu/ATG | RAEB-T (3) | 3/5 | 1/5 | Dresden, Germany |
RAEB (1) | ||||||
Third PR (1) | ||||||
Abbreviations: Bu, busulfan; ATG, antithymocyte globulin; Flag/Ida, fludarabine, cytosine arabinoside, G-CSF, and idarubicin; RAEB-T, refractory anemia with excess blasts in transformation |
140 or 180 mg/m2