Table 1. Poly(I:C) stimulation leads to... | American Society of Hematology

Table 1.

Poly(I:C) stimulation leads to phenotype changes in PMCs

	% PMCs			MFI
	–	pIC	–	pIC
I-A/E	16.6 ± 3.8	92.1 ± 2.2^*	944 ± 174	2594 ± 832†
CD80	30.1 ± 7.9	92.7 ± 2.0^*	205 ± 14	1366 ± 208^*
CD28	3.3 ± 1.3	36.3 ± 9.7†	174 ± 83	89 ± 60
CD21/35	15.8 ± 3.4	76.9 ± 7.1^*	56 ± 4	195 ± 32^*
FcγRII/III
High	80.1 ± 3.5	92.3 ± 2.2†	453 ± 15	1391 ± 122^*
Intermediate	18.1 ± 3.0	7.5 ± 2.2†	150 ± 7	115 ± 6†

	% PMCs			MFI
	–	pIC	–	pIC
I-A/E	16.6 ± 3.8	92.1 ± 2.2^*	944 ± 174	2594 ± 832†
CD80	30.1 ± 7.9	92.7 ± 2.0^*	205 ± 14	1366 ± 208^*
CD28	3.3 ± 1.3	36.3 ± 9.7†	174 ± 83	89 ± 60
CD21/35	15.8 ± 3.4	76.9 ± 7.1^*	56 ± 4	195 ± 32^*
FcγRII/III
High	80.1 ± 3.5	92.3 ± 2.2†	453 ± 15	1391 ± 122^*
Intermediate	18.1 ± 3.0	7.5 ± 2.2†	150 ± 7	115 ± 6†

Peritoneal MCs were gated for expression of c-Kit and FcϵRI or S/T2 and determined as 100%. Expression of MHC class II molecules, costimulatory molecules, and complement receptors were analyzed. Peritoneal MCs from 4 to 10 mice each were analyzed.

–

indicates before stimulation

P < .001

†

P < .05

View Large

This Feature Is Available To Subscribers Only