Table 1.

The highest-scored VH3-21+-related genes in different comparisons

Probe ID
GenBank no.
LocusLink no.
Gene name
Comparison*
Up-regulated in VH3-21 + B-CLL (VH3-21-related)     
35566_f_at   —   3502, 3507   VH3-23 gene†   1,2,LDA,WV  
34105_f_at   —   3492, 3500, 3502, 3507, 388255   VH3 family gene (either the VH3-21, VH3-07 or VH3-74 gene)†   1,2,LDA,WV  
391_at   X89416   5536  PPP5C: protein phosphatase 5   1,2,WV  
810_at   U64105   9138  ARHGEFI: Rho guanine nucleotide exchange factor (GEF) 1   1,2,WV  
33818_at   AC004472   7415  VCP: valosin-containing protein   1,2,WV  
40198_at   L06132   7416  VDACI: voltage-dependent anion channel 1   1,2,WV  
1505_at  NM_001071  7298  TYMS: thymidylate synthetase   1,2,WV  
37753_at   U66617   6602  SMARCDI: SW1/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1   1,2,WV  
1703_g_at  NM_001950  1874  E2FR: E2F transcription factor 4, p107/p130-binding   1,WV  
39190_s_at   AC002126   284439  MGC26694: hypothetical protein MGC26694  1,WV  
40539_at   U42391   4650  MYO9B: myosin IXB   1,WV  
39533_at   D87432   9057  SLC7A6: solute carrier family 7 (cationic amino acid transporter, y+ system), member 6   1,WV  
39704_s_at   L17131   3159  HMGA1: high mobility group AT-hook 1   1,WV  
32844_at   AF104913   1981  EIF4G1: eukaryotic translation initiation factor 4 gamma, 1   1,2  
1306_at   D12686   1981    2  
33268_at   L25270   8242  SMCX: Smcx homolog, X-linked (mouse)   1,2  
38259_at   AB002559   6813  STXBP2: syntaxin binding protein 2   1  
1760_s_at   D11327   5778  PTPN7: protein tyrosine phosphatase, non-receptor type 7   1  
41753_at   U48734   81  ACTN4: actinin, alpha 4   1  
34325_at   AJ005893   10084  PQBP1: polyglutamine binding protein 1   2  
34868_at   AB029012   23381  EST1B: Est1p-like protein B   1  
591_s_at   M33684   5770  PTPN1: protein tyrosine phosphatase, nonreceptor type 1   1  
1553_r_at   U22028   1553  CYP2A13: cytochrome P450, family 2, subfamily A, polypeptide 13   2  
38522_s_at   X52785   933  CD22: CD22 antigen   2  
2009_at   U33284   2185  PTK2B: PTK2B protein tyrosine kinase 2 beta   2  
1994_f_at   AF001359   4292  MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (Escherichia coli)   2  
35620_at   AF043250   10452  TOMM40: translocase of outer mitochondrial membrane 40 homolog (yeast)   2  
37095_r_at   M84562   2358  FPRL1: formyl peptide receptor-like 1   2  
40324_r_at   AF070585   8940  TOP3B: topoisomerase (DNA) III beta   2  
36094_at   M21984   7140  TNNT3: troponin T3, skeletal, fast   2  
Down-regulated in VH3-21+ B-CLL (non-VH3-21-related)     
41796_at   AB029015   23228  PLCL2: phospholipase C-like 2   1,2‡,LDA,WV  
32172_at   AL096858   23013  SHARP: SMART/HDAC1-assocjated repressor protein   1,2§,WV  
33859_at   U96915   10284  SAP18: sin3-associated polypeptide, 18kDa   1,LDA,WV  
36938_at   U70063   427  ASAH1: N-acylsphingosine amidohydrolase (acid ceramidase) 1   1,LDA,WV  
32554_s_at   Y12781   6907  TBL1X: transducin (beta)-like 1X-linked   1,LDA,WV  
33847_s_at   A1304854   1027  CDKN1B: cyclin-dependent kinase inhibitor 1B (p27, Kip1)   1,LDA,WV  
38380_at   Y18863   10775  POP4: POP4 (processing of precursor, Saccharomyces cerevisiae) homolog   1,WV  
36827_at   AF020762   64746  ACBD3: acyl-coenzyme A binding domain containing 3   1,WV  
1453_at   U68018   4087  MADH2: MAD, mothers against decapentaplegic homolog 2 (Drosophila)  1,WV  
41202_s_at   AF000152   10106  CTDSP2: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A)   1,WV  
36031_at   AB024401   3621  ING1: inhibitor of growth family, member 1   1,WV  
32696_at   X59841   5090  PBX3: pre-B-cell leukemia transcription factor 3   1,WV  
39434_at   AB011164   253725  KIAA0592: KIAA0592 protein   1,WV  
39345_at   AI525834   10577  NPC2: Niemann-Pick disease, type C2   1,LDA  
654_at   L07648   4601  MXI1: MAX interacting protein 1   1,LDA  
36894_at   AL031846   23492  CBX7: chromobox homolog 7   2‡,LDA  
36502_at   AB020641   5218  PFTK1: PFTAIRE protein kinase 1   2‡,LDA  
35811_at   AF037204   11342  RNF13: ring finger protein 13   1  
37035_at   AI557272   27230  SERP1: stress-associated endoplasmic reticulum protein 1   1  
1452_at   U24576   8543  LMO4: LIM domain only 4   1  
41379_at   AB011166   23137  SMC5L1: SMC5 structural maintenance of chromosomes 5-like 1 (yeast)   1  
40063_at   U22897   10241  NDP52: nuclear domain 10 protein   1  
37253_at   X92493   8395  PIP5K1B: phosphatidylinositol-4-phosphate 5-kinase, type 1, beta   2§  
35145_at   X96401   4335  MNT: MAX-binding protein   2§  
1797_at   U40343   1032  CDKN2D: cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)   2§  
943_at
 		 D43968
 		 861
 		RUNX1: runt-related transcription factor 1 (acute myeloid leukemia 1; aml 1 oncogene)
 		 2§
 
Probe ID
GenBank no.
LocusLink no.
Gene name
Comparison*
Up-regulated in VH3-21 + B-CLL (VH3-21-related)     
35566_f_at   —   3502, 3507   VH3-23 gene†   1,2,LDA,WV  
34105_f_at   —   3492, 3500, 3502, 3507, 388255   VH3 family gene (either the VH3-21, VH3-07 or VH3-74 gene)†   1,2,LDA,WV  
391_at   X89416   5536  PPP5C: protein phosphatase 5   1,2,WV  
810_at   U64105   9138  ARHGEFI: Rho guanine nucleotide exchange factor (GEF) 1   1,2,WV  
33818_at   AC004472   7415  VCP: valosin-containing protein   1,2,WV  
40198_at   L06132   7416  VDACI: voltage-dependent anion channel 1   1,2,WV  
1505_at  NM_001071  7298  TYMS: thymidylate synthetase   1,2,WV  
37753_at   U66617   6602  SMARCDI: SW1/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1   1,2,WV  
1703_g_at  NM_001950  1874  E2FR: E2F transcription factor 4, p107/p130-binding   1,WV  
39190_s_at   AC002126   284439  MGC26694: hypothetical protein MGC26694  1,WV  
40539_at   U42391   4650  MYO9B: myosin IXB   1,WV  
39533_at   D87432   9057  SLC7A6: solute carrier family 7 (cationic amino acid transporter, y+ system), member 6   1,WV  
39704_s_at   L17131   3159  HMGA1: high mobility group AT-hook 1   1,WV  
32844_at   AF104913   1981  EIF4G1: eukaryotic translation initiation factor 4 gamma, 1   1,2  
1306_at   D12686   1981    2  
33268_at   L25270   8242  SMCX: Smcx homolog, X-linked (mouse)   1,2  
38259_at   AB002559   6813  STXBP2: syntaxin binding protein 2   1  
1760_s_at   D11327   5778  PTPN7: protein tyrosine phosphatase, non-receptor type 7   1  
41753_at   U48734   81  ACTN4: actinin, alpha 4   1  
34325_at   AJ005893   10084  PQBP1: polyglutamine binding protein 1   2  
34868_at   AB029012   23381  EST1B: Est1p-like protein B   1  
591_s_at   M33684   5770  PTPN1: protein tyrosine phosphatase, nonreceptor type 1   1  
1553_r_at   U22028   1553  CYP2A13: cytochrome P450, family 2, subfamily A, polypeptide 13   2  
38522_s_at   X52785   933  CD22: CD22 antigen   2  
2009_at   U33284   2185  PTK2B: PTK2B protein tyrosine kinase 2 beta   2  
1994_f_at   AF001359   4292  MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (Escherichia coli)   2  
35620_at   AF043250   10452  TOMM40: translocase of outer mitochondrial membrane 40 homolog (yeast)   2  
37095_r_at   M84562   2358  FPRL1: formyl peptide receptor-like 1   2  
40324_r_at   AF070585   8940  TOP3B: topoisomerase (DNA) III beta   2  
36094_at   M21984   7140  TNNT3: troponin T3, skeletal, fast   2  
Down-regulated in VH3-21+ B-CLL (non-VH3-21-related)     
41796_at   AB029015   23228  PLCL2: phospholipase C-like 2   1,2‡,LDA,WV  
32172_at   AL096858   23013  SHARP: SMART/HDAC1-assocjated repressor protein   1,2§,WV  
33859_at   U96915   10284  SAP18: sin3-associated polypeptide, 18kDa   1,LDA,WV  
36938_at   U70063   427  ASAH1: N-acylsphingosine amidohydrolase (acid ceramidase) 1   1,LDA,WV  
32554_s_at   Y12781   6907  TBL1X: transducin (beta)-like 1X-linked   1,LDA,WV  
33847_s_at   A1304854   1027  CDKN1B: cyclin-dependent kinase inhibitor 1B (p27, Kip1)   1,LDA,WV  
38380_at   Y18863   10775  POP4: POP4 (processing of precursor, Saccharomyces cerevisiae) homolog   1,WV  
36827_at   AF020762   64746  ACBD3: acyl-coenzyme A binding domain containing 3   1,WV  
1453_at   U68018   4087  MADH2: MAD, mothers against decapentaplegic homolog 2 (Drosophila)  1,WV  
41202_s_at   AF000152   10106  CTDSP2: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A)   1,WV  
36031_at   AB024401   3621  ING1: inhibitor of growth family, member 1   1,WV  
32696_at   X59841   5090  PBX3: pre-B-cell leukemia transcription factor 3   1,WV  
39434_at   AB011164   253725  KIAA0592: KIAA0592 protein   1,WV  
39345_at   AI525834   10577  NPC2: Niemann-Pick disease, type C2   1,LDA  
654_at   L07648   4601  MXI1: MAX interacting protein 1   1,LDA  
36894_at   AL031846   23492  CBX7: chromobox homolog 7   2‡,LDA  
36502_at   AB020641   5218  PFTK1: PFTAIRE protein kinase 1   2‡,LDA  
35811_at   AF037204   11342  RNF13: ring finger protein 13   1  
37035_at   AI557272   27230  SERP1: stress-associated endoplasmic reticulum protein 1   1  
1452_at   U24576   8543  LMO4: LIM domain only 4   1  
41379_at   AB011166   23137  SMC5L1: SMC5 structural maintenance of chromosomes 5-like 1 (yeast)   1  
40063_at   U22897   10241  NDP52: nuclear domain 10 protein   1  
37253_at   X92493   8395  PIP5K1B: phosphatidylinositol-4-phosphate 5-kinase, type 1, beta   2§  
35145_at   X96401   4335  MNT: MAX-binding protein   2§  
1797_at   U40343   1032  CDKN2D: cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)   2§  
943_at
 		 D43968
 		 861
 		RUNX1: runt-related transcription factor 1 (acute myeloid leukemia 1; aml 1 oncogene)
 		 2§
 
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