Plasma and RBC volumes in rats
. | Vehicle . | E2, 1 mg/kg . |
|---|---|---|
| Body weight, g | ||
| Basal Diet | 189.8 ± 3.8 | 162.0 ± 5.4* |
| Low-Iron Diet | 174.8 ± 8.9† | 157.2 ± 7.9* |
| Hematocrit, % | ||
| Basal Diet | 45.4 ± 3.4 | 40.7 ± 2.0* |
| Low-Iron Diet | 43.5 ± 2.7 | 41.8 ± 5.0 |
| Plasma volume, mL | ||
| Basal Diet | 8.1 ± 1.2 | 9.4 ± 2.1 |
| Low-Iron Diet | 7.7 ± 1.1 | 9.7 ± 3.0 |
| Plasma volume/body weight, mL/kg | ||
| Basal Diet | 42.8 ± 6.2 | 57.9 ± 13.3* |
| Low-Iron Diet | 44.3 ± 7.3 | 61.7 ± 17.4 |
| RBC volume, mL | ||
| Basal Diet | 6.7 ± 0.7 | 6.5 ± 2.0 |
| Low-Iron Diet | 5.9 ± 0.8 | 6.9 ± 1.8 |
| RBC volume/body weight, mL/kg | ||
| Basal Diet | 35.5 ± 3.8 | 40.4 ± 12.5 |
| Low-Iron Diet | 34.0 ± 4.6 | 43.9 ± 10.4 |
. | Vehicle . | E2, 1 mg/kg . |
|---|---|---|
| Body weight, g | ||
| Basal Diet | 189.8 ± 3.8 | 162.0 ± 5.4* |
| Low-Iron Diet | 174.8 ± 8.9† | 157.2 ± 7.9* |
| Hematocrit, % | ||
| Basal Diet | 45.4 ± 3.4 | 40.7 ± 2.0* |
| Low-Iron Diet | 43.5 ± 2.7 | 41.8 ± 5.0 |
| Plasma volume, mL | ||
| Basal Diet | 8.1 ± 1.2 | 9.4 ± 2.1 |
| Low-Iron Diet | 7.7 ± 1.1 | 9.7 ± 3.0 |
| Plasma volume/body weight, mL/kg | ||
| Basal Diet | 42.8 ± 6.2 | 57.9 ± 13.3* |
| Low-Iron Diet | 44.3 ± 7.3 | 61.7 ± 17.4 |
| RBC volume, mL | ||
| Basal Diet | 6.7 ± 0.7 | 6.5 ± 2.0 |
| Low-Iron Diet | 5.9 ± 0.8 | 6.9 ± 1.8 |
| RBC volume/body weight, mL/kg | ||
| Basal Diet | 35.5 ± 3.8 | 40.4 ± 12.5 |
| Low-Iron Diet | 34.0 ± 4.6 | 43.9 ± 10.4 |
The rats were administered E2 at 1 mg/kg 3 times a week for 2 months and fed the Basal Diet 5755 (vehicle group, N = 5; E2, N = 7) or the Low-Iron Purified Diet (vehicle group, n = 6; E2 group, n = 5) from TestDiet. Data are presented as mean ± SD.
P < .05 (compared with vehicle group).
P < .05 (compared with Basal Diet group).