Estimated HRs and the corresponding confidence intervals for the main end points
End point . | Group B vs group A (97.5% CI) . | Group D vs group C (97.5% CI) . | Groups B + D vs groups A + C (95% CI) . | Group C vs group A (97.5% CI) . | Group D vs group B (97.5% CI) . | Groups C + D vs groups A + B (95% CI) . |
|---|---|---|---|---|---|---|
| OS | 0.95 (0.74-1.23) | 0.87 (0.67-1.12) | 0.91 (0.78-1.02) | 1.03 (0.79-1.32) | 0.94 (0.72-1.21) | 0.98 (0.84-1.15) |
| EFS | 0.98 (0.76-1.25) | 0.86 (0.67-1.10) | 0.92 (0.79-1.07) | 1.00 (0.78-1.28) | 0.88 (0.69-1.13) | 0.94 (0.81-1.09) |
| DFS from CR | 1.03 (0.72-1.48) | 1.05 (0.75-1.48) | 1.04 (0.84-1.30) | 0.99 (0.68-1.44) | 1.01 (0.72-1.41) | 1.00 (0.81-1.24) |
| Survival from CR | 1.00 (0.68-1.46) | 1.01 (0.71-1.44) | 1.00 (0.80-1.26) | 1.08 (0.73-1.58) | 1.11 (0.78-1.57) | 1.09 (0.87-1.37) |
End point . | Group B vs group A (97.5% CI) . | Group D vs group C (97.5% CI) . | Groups B + D vs groups A + C (95% CI) . | Group C vs group A (97.5% CI) . | Group D vs group B (97.5% CI) . | Groups C + D vs groups A + B (95% CI) . |
|---|---|---|---|---|---|---|
| OS | 0.95 (0.74-1.23) | 0.87 (0.67-1.12) | 0.91 (0.78-1.02) | 1.03 (0.79-1.32) | 0.94 (0.72-1.21) | 0.98 (0.84-1.15) |
| EFS | 0.98 (0.76-1.25) | 0.86 (0.67-1.10) | 0.92 (0.79-1.07) | 1.00 (0.78-1.28) | 0.88 (0.69-1.13) | 0.94 (0.81-1.09) |
| DFS from CR | 1.03 (0.72-1.48) | 1.05 (0.75-1.48) | 1.04 (0.84-1.30) | 0.99 (0.68-1.44) | 1.01 (0.72-1.41) | 1.00 (0.81-1.24) |
| Survival from CR | 1.00 (0.68-1.46) | 1.01 (0.71-1.44) | 1.00 (0.80-1.26) | 1.08 (0.73-1.58) | 1.11 (0.78-1.57) | 1.09 (0.87-1.37) |
* Only patients who achieved CR were considered (the number of patients in each group is given in Table 2).