Evaluation of Hb, hematologic variables (RBCs, MCV, MCHC, absolute reticulocyte count), and iron parameters (serum iron and ferritin) in 95 control subjects and in 91 patients with epithelial ovarian cancer according to stage
Parameters . | Control subjects . | Stages I-II, n = 25 . | Stages III-IV, n = 66 . | P* . |
|---|---|---|---|---|
| Hb, g/dL | 12.4 ± 1.1 | 12.7 ± 1.1 | 10.0 ± 1.1† | < .001 |
| RBCs, 106/mL | 4.52 ± 0.3 | 4.4 ± 0.5 | 4.0 ± 0.4† | < .001 |
| MCV, fL | 87.3 ± 4.7 | 87.1 ± 6.1 | 84.7 ± 4.3† | .038 |
| MCHC, g/dL | 33.3 ± 1.5 | 33.1 ± 1.6 | 32.8 ± 2.1 | .520 |
| Reticulocytes, % | 1.35 ± 0.4 | 1.43 ± 0.4 | 0.88 ± 0.5† | < .001 |
| Reticulocytes, 103/mL | 63.6 ± 12.1 | 62.7 ± 17.9 | 39.2 ± 25.8† | < .001 |
| Serum iron, μg/dL | 93.4 ± 20.5 | 87.8 ± 33.5 | 49.3 ± 19.8† | < .001 |
| Ferritin, ng/mL | 56 ± 19 | 58 ± 32.9 | 320.4 ± 142.7† | < .001 |
Parameters . | Control subjects . | Stages I-II, n = 25 . | Stages III-IV, n = 66 . | P* . |
|---|---|---|---|---|
| Hb, g/dL | 12.4 ± 1.1 | 12.7 ± 1.1 | 10.0 ± 1.1† | < .001 |
| RBCs, 106/mL | 4.52 ± 0.3 | 4.4 ± 0.5 | 4.0 ± 0.4† | < .001 |
| MCV, fL | 87.3 ± 4.7 | 87.1 ± 6.1 | 84.7 ± 4.3† | .038 |
| MCHC, g/dL | 33.3 ± 1.5 | 33.1 ± 1.6 | 32.8 ± 2.1 | .520 |
| Reticulocytes, % | 1.35 ± 0.4 | 1.43 ± 0.4 | 0.88 ± 0.5† | < .001 |
| Reticulocytes, 103/mL | 63.6 ± 12.1 | 62.7 ± 17.9 | 39.2 ± 25.8† | < .001 |
| Serum iron, μg/dL | 93.4 ± 20.5 | 87.8 ± 33.5 | 49.3 ± 19.8† | < .001 |
| Ferritin, ng/mL | 56 ± 19 | 58 ± 32.9 | 320.4 ± 142.7† | < .001 |
Data are reported as mean ± standard deviation (SD). Hb indicates hemoglobin; RBCs, red blood cells; MCV, mean cell volume; MCHC, mean cell hemoglobin concentration.
P value was calculated with Student t test (patients with stages III-IV vs patients with stages I-II)
P < .05 in comparison to control subjects