Adverse events of at least grade 3 intensity occurring in patients at the recommended dose level of bortezomib and PegLD
Cycle no. (n)* . | Adverse event (n)† . |
|---|---|
| 1 (16) | Detailed in the section, “Adverse events” |
| 2 (10) | Allergic reaction (1), hypertension (1), hyponatremia (1), neutropenia (1), pneumonia (1), lymphopenia (2), thrombocytopenia (4) |
| 3 (10) | Hypertension (1), hyponatremia (1), peripheral neuropathy/impotence (1), pneumonia (1), lymphopenia (5), thrombocytopenia (5) |
| 4 (9) | Clostridium difficile infection (1), confusion (1), diarrhea (1), hypertension (1), sinusitis (1), vein thrombosis (1), peripheral neuropathy (2), thrombocytopenia (4), lymphopenia (5) |
| 5 (6) | Diarrhea (1), fever (1), thrombocytopenia (2), lymphopenia (3) |
| 6 (6) | Anorexia (1), thrombocytopenia (1), fatigue (1), lymphopenia (3) |
| 7 (3) | Diarrhea (1), lymphopenia (1) |
| 8 (2) | Lymphopenia (2) |
Cycle no. (n)* . | Adverse event (n)† . |
|---|---|
| 1 (16) | Detailed in the section, “Adverse events” |
| 2 (10) | Allergic reaction (1), hypertension (1), hyponatremia (1), neutropenia (1), pneumonia (1), lymphopenia (2), thrombocytopenia (4) |
| 3 (10) | Hypertension (1), hyponatremia (1), peripheral neuropathy/impotence (1), pneumonia (1), lymphopenia (5), thrombocytopenia (5) |
| 4 (9) | Clostridium difficile infection (1), confusion (1), diarrhea (1), hypertension (1), sinusitis (1), vein thrombosis (1), peripheral neuropathy (2), thrombocytopenia (4), lymphopenia (5) |
| 5 (6) | Diarrhea (1), fever (1), thrombocytopenia (2), lymphopenia (3) |
| 6 (6) | Anorexia (1), thrombocytopenia (1), fatigue (1), lymphopenia (3) |
| 7 (3) | Diarrhea (1), lymphopenia (1) |
| 8 (2) | Lymphopenia (2) |