Distribution of pretreatment risk factors by randomized postremission regimen
. | HiDAC alone, no. (%) . | Multiagent CT, no. (%) . | Total, no. (%) . |
---|---|---|---|
Age, y | |||
Younger than 30 | 36 (24) | 30 (19) | 66 (21) |
30-39 | 34 (22) | 36 (23) | 70 (23) |
40-49 | 44 (29) | 52 (33) | 96 (31) |
50-59 | 39 (25) | 38 (24) | 77 (25) |
WBC count, × 103/μL | |||
7 or lower | 52 (35) | 44 (29) | 96 (32) |
7.1-30 | 42 (28) | 50 (32) | 92 (30) |
Greater than 30 | 56 (37) | 60 (38) | 116 (38) |
CD56 | |||
Negative | 84 (90) | 86 (84) | 170 (87) |
Positive | 9 (10) | 16 (16) | 25 (13) |
Cytogenetic risk groups (cumulative incidence of relapse)* | |||
Favorable | 27 (18) | 21 (13) | 48 (16) |
Intermediate | 54 (35) | 66 (42) | 120 (39) |
Unfavorable | 11 (7) | 4 (3) | 15 (5) |
Not classified† | 5 (3) | 5 (3) | 10 (3) |
t(15;17) | 5 (3) | 4 (3) | 9 (3) |
Inadequate | 51 (33) | 56 (36) | 107 (35) |
FAB | |||
Non-M4 or M5 | 108 (71) | 102 (65) | 210 (68) |
M4 or M5 | 45 (29) | 54 (35) | 99 (32) |
. | HiDAC alone, no. (%) . | Multiagent CT, no. (%) . | Total, no. (%) . |
---|---|---|---|
Age, y | |||
Younger than 30 | 36 (24) | 30 (19) | 66 (21) |
30-39 | 34 (22) | 36 (23) | 70 (23) |
40-49 | 44 (29) | 52 (33) | 96 (31) |
50-59 | 39 (25) | 38 (24) | 77 (25) |
WBC count, × 103/μL | |||
7 or lower | 52 (35) | 44 (29) | 96 (32) |
7.1-30 | 42 (28) | 50 (32) | 92 (30) |
Greater than 30 | 56 (37) | 60 (38) | 116 (38) |
CD56 | |||
Negative | 84 (90) | 86 (84) | 170 (87) |
Positive | 9 (10) | 16 (16) | 25 (13) |
Cytogenetic risk groups (cumulative incidence of relapse)* | |||
Favorable | 27 (18) | 21 (13) | 48 (16) |
Intermediate | 54 (35) | 66 (42) | 120 (39) |
Unfavorable | 11 (7) | 4 (3) | 15 (5) |
Not classified† | 5 (3) | 5 (3) | 10 (3) |
t(15;17) | 5 (3) | 4 (3) | 9 (3) |
Inadequate | 51 (33) | 56 (36) | 107 (35) |
FAB | |||
Non-M4 or M5 | 108 (71) | 102 (65) | 210 (68) |
M4 or M5 | 45 (29) | 54 (35) | 99 (32) |