FAB classification and hematologic values at study entry
. | No. patients (%) . |
|---|---|
| FAB classification | |
| M0 | 15 (3) |
| M1 | 55 (12) |
| M2 | 154 (33) |
| M2Eo | 12 (3) |
| M3 | 12 (3) |
| M3V | 11 (2) |
| M4 | 81 (17) |
| M4Eo | 17 (4) |
| M5A | 23 (5) |
| M5B | 27 (6) |
| M6 | 12 (3) |
| M7 | 4 (1) |
| AML, not specified | 24 (5) |
| L1 | 1 (< 1) |
| Unclassifiable AL | 5 (1) |
| Undifferentiated AL | 1 (< 1) |
| MDS | 1 (< 1) |
| RAEBT | 8 (2) |
| Not evaluable | 10 (2) |
| Total | 473 (100) |
| Hematologic values | |
| Hemoglobin level, g/dL | |
| 2.8-7.9 | 138 (30) |
| 8.0-9.9 | 196 (43) |
| Greater than 10.0 | 124 (27) |
| Platelet count, × 103/μL | |
| 7-50 | 239 (51) |
| 51-99 | 134 (29) |
| Greater than 100 | 95 (20) |
| WBC count, × 103/μL | |
| 0.1-7.0 | 154 (33) |
| 7.1-30.0 | 130 (28) |
| Greater than 30.0 | 184 (39) |
. | No. patients (%) . |
|---|---|
| FAB classification | |
| M0 | 15 (3) |
| M1 | 55 (12) |
| M2 | 154 (33) |
| M2Eo | 12 (3) |
| M3 | 12 (3) |
| M3V | 11 (2) |
| M4 | 81 (17) |
| M4Eo | 17 (4) |
| M5A | 23 (5) |
| M5B | 27 (6) |
| M6 | 12 (3) |
| M7 | 4 (1) |
| AML, not specified | 24 (5) |
| L1 | 1 (< 1) |
| Unclassifiable AL | 5 (1) |
| Undifferentiated AL | 1 (< 1) |
| MDS | 1 (< 1) |
| RAEBT | 8 (2) |
| Not evaluable | 10 (2) |
| Total | 473 (100) |
| Hematologic values | |
| Hemoglobin level, g/dL | |
| 2.8-7.9 | 138 (30) |
| 8.0-9.9 | 196 (43) |
| Greater than 10.0 | 124 (27) |
| Platelet count, × 103/μL | |
| 7-50 | 239 (51) |
| 51-99 | 134 (29) |
| Greater than 100 | 95 (20) |
| WBC count, × 103/μL | |
| 0.1-7.0 | 154 (33) |
| 7.1-30.0 | 130 (28) |
| Greater than 30.0 | 184 (39) |
The FAB classification is based on central review when available (n = 439), otherwise on local institutional assessment. Hemoglobin levels, obtained in 458 patients, had a median level of 8.8 g/dL (range, 2.8-15.0 g/dL). Platelet counts were done in 468 patients, with a median count of 48 × 103/μL (range, 7-460 × 103/μL). WBC counts from 465 patients had a median value of 16.9 × 103/μL (range, 0.1-447.0 × 103/μL).
AL indicates acute leukemia; MDS, myelodysplastic syndrome; RAEBT, refractory anemia with excess blasts in transformation.