CD38 ligation in the presence of IL-2 is not followed by sCD100 release
. | 16 h, IU/mL . | . | . | . | 5 d, IU/mL . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient . | Basal . | Anti-CD38 + IL-2 . | Anti-CD38 . | IL-2 . | Basal . | Anti-CD38 + IL-2 . | Anti-CD38 . | IL-2 . | ||||||
| 2 | 0.923 | 0 | 0 | 0.698 | 0 | 0 | 0 | 0 | ||||||
| 4 | 0 | 1.01 | 0 | 0 | 2.9 | 5.1 | 4.4 | 4.7 | ||||||
| 6 | 12.4 | 9.4 | 8.2 | 12.5 | 2.12 | 0 | 0.8 | 0 | ||||||
| 12 | 0 | 1.41 | 1.6 | 0 | 2.1 | 0 | 0.8 | 0 | ||||||
. | 16 h, IU/mL . | . | . | . | 5 d, IU/mL . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient . | Basal . | Anti-CD38 + IL-2 . | Anti-CD38 . | IL-2 . | Basal . | Anti-CD38 + IL-2 . | Anti-CD38 . | IL-2 . | ||||||
| 2 | 0.923 | 0 | 0 | 0.698 | 0 | 0 | 0 | 0 | ||||||
| 4 | 0 | 1.01 | 0 | 0 | 2.9 | 5.1 | 4.4 | 4.7 | ||||||
| 6 | 12.4 | 9.4 | 8.2 | 12.5 | 2.12 | 0 | 0.8 | 0 | ||||||
| 12 | 0 | 1.41 | 1.6 | 0 | 2.1 | 0 | 0.8 | 0 | ||||||
Quantification of sCD100 in culture supernatants from 4 different patients harvested after 16 hours or 5 days, respectively.