Table 4.

Relapse and overall survival by TCR status or genotype




Cumulative incidence of relapse, 4-y estimates, % (95% CI)

Overall survival, 4-y estimates, % (95% CI)
All patients   60 (50-71)   44 (33-54)  
TCR subsets   
    Immature   56 (36-76)   30 (14-49)  
    Pre-αβ   59 (42-77)   59* (38-75)  
    TCR+  66 (49-82)   30 (14-48)  
Genotype subsets   
    CALM-AF10  57 (27-90)   42 (6-77)  
    SIL-TAL1  82 (56-97)   45 (17-71)  
    HOX11  45 (22-77)   56 (20-80)  
    HOX11L2  83 (48-99)   11 (1-40)  
Others   55 (39-71)   45 (28-61)  
    TAL1  62 (42-82)   39 (18-60)  
    LYL  NE   NE  
    LMO2
 
68 (42-85)
 
29 (8-55)
 



Cumulative incidence of relapse, 4-y estimates, % (95% CI)

Overall survival, 4-y estimates, % (95% CI)
All patients   60 (50-71)   44 (33-54)  
TCR subsets   
    Immature   56 (36-76)   30 (14-49)  
    Pre-αβ   59 (42-77)   59* (38-75)  
    TCR+  66 (49-82)   30 (14-48)  
Genotype subsets   
    CALM-AF10  57 (27-90)   42 (6-77)  
    SIL-TAL1  82 (56-97)   45 (17-71)  
    HOX11  45 (22-77)   56 (20-80)  
    HOX11L2  83 (48-99)   11 (1-40)  
Others   55 (39-71)   45 (28-61)  
    TAL1  62 (42-82)   39 (18-60)  
    LYL  NE   NE  
    LMO2
 
68 (42-85)
 
29 (8-55)
 

NE indicates not estimated.

*

P = .02 by the log-rank test.

P = .05 by the Gray test.

P = .003 by the log-rank test.

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