Comparison of uveitogenic, lymphoproliferative, and chemotactic effects of IRBP peptide fragments between mouse strains
Strain and parameter . | Peptide 1-20 . | Peptide 161-180 . | Reference . |
|---|---|---|---|
| B10.RIII (H-2r) | |||
| EAU (pathogenicity) | — | ++ | |
| Lymphocyte proliferation (antigenicity) | — | ++ | Silver et al27 |
| Chemotaxis | ++ | + | Figure 7B |
| C57BL/6 (H-2b) | |||
| EAU (pathogenicity) | + | — | |
| Lymphocyte proliferation (antigenicity) | + | + | Avichezer et al28 |
| Chemotaxis | ++ | + | Figure 7B |
Strain and parameter . | Peptide 1-20 . | Peptide 161-180 . | Reference . |
|---|---|---|---|
| B10.RIII (H-2r) | |||
| EAU (pathogenicity) | — | ++ | |
| Lymphocyte proliferation (antigenicity) | — | ++ | Silver et al27 |
| Chemotaxis | ++ | + | Figure 7B |
| C57BL/6 (H-2b) | |||
| EAU (pathogenicity) | + | — | |
| Lymphocyte proliferation (antigenicity) | + | + | Avichezer et al28 |
| Chemotaxis | ++ | + | Figure 7B |
— indicates no response; + indicates positive response.