Table 3. Induction of complete donor... | American Society of Hematology

Table 3.

Induction of complete donor chimerism is similar in arthritic and healthy mice

	Mean donor cells ± SEM, %
	PB	SP	LN	BM
CD4⁺ T cells
Healthy	99.6 ± 0.1	99.1 ± 0.2	98.9 ± 0.5	99.7 ± 0.1
Arthritic	99.3 ± 0.3	99.2 ± 0.2	99.1 ± 0.2	99.2 ± 0.4
CD8⁺ T cells
Healthy	98.3 ± 1.2	99.0 ± 0.4	98.1 ± 0.7	99.4 ± 0.3
Arthritic	98.8 ± 0.6	98.8 ± 0.3	97.7 ± 0.7	99.3 ± 0.3
B cells
Healthy	99.6 ± 0.1	99.7 ± 0.1	99.2 ± 0.2	99.4 ± 0.2
Arthritic	99.7 ± 0.1	99.7 ± 0.1	99.3 ± 0.2	99.8 ± 0.1
Granulocytes
Healthy	97.4 ± 1.3	98.2 ± 0.4	NA	92.8 ± 1.4
Arthritic	98.4 ± 0.3	98.4 ± 0.4	NA	93.7 ± 1.2

	Mean donor cells ± SEM, %
	PB	SP	LN	BM
CD4⁺ T cells
Healthy	99.6 ± 0.1	99.1 ± 0.2	98.9 ± 0.5	99.7 ± 0.1
Arthritic	99.3 ± 0.3	99.2 ± 0.2	99.1 ± 0.2	99.2 ± 0.4
CD8⁺ T cells
Healthy	98.3 ± 1.2	99.0 ± 0.4	98.1 ± 0.7	99.4 ± 0.3
Arthritic	98.8 ± 0.6	98.8 ± 0.3	97.7 ± 0.7	99.3 ± 0.3
B cells
Healthy	99.6 ± 0.1	99.7 ± 0.1	99.2 ± 0.2	99.4 ± 0.2
Arthritic	99.7 ± 0.1	99.7 ± 0.1	99.3 ± 0.2	99.8 ± 0.1
Granulocytes
Healthy	97.4 ± 1.3	98.2 ± 0.4	NA	92.8 ± 1.4
Arthritic	98.4 ± 0.3	98.4 ± 0.4	NA	93.7 ± 1.2

Percentages of donor cells were analyzed using FACS in different cell lineages (ie, CD3⁺ T cells, B220⁺ B cells, and Gr1⁺ granulocytes) in the following lymphoid compartments: peripheral blood (PB), spleen (SP), lymph node (LN), and bone marrow (BM). Values are expressed as mean ± SEM (n = 8 mice per group). NA indicates not available because of low numbers of Gr-1⁺ cells in lymph nodes.

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