Effect of cell vaccines on development of MRD in mice
Vaccine . | No. of mice . | No. of MRD+ mice (%) . |
|---|---|---|
| DA1-3b/CXCL10 | 65 | 0 (0) |
| BA1-3b/Zeo | 8 | 6 (62.5) |
| DA1-3b/IL12 | 47 | 9 (19) |
| DA1-3b/CD150 | 26 | 22 (85) |
Vaccine . | No. of mice . | No. of MRD+ mice (%) . |
|---|---|---|
| DA1-3b/CXCL10 | 65 | 0 (0) |
| BA1-3b/Zeo | 8 | 6 (62.5) |
| DA1-3b/IL12 | 47 | 9 (19) |
| DA1-3b/CD150 | 26 | 22 (85) |
Mice were vaccinated with irradiated DA1-3b cells transduced with vector containing IL-12 (DA1-3b/IL12), CXCL10 (DA1-3b/CXCL10), CD154 (DA1-3b/CD154), or control empty vector (DA1-3b/Zeo) and then inoculated with 104 live DA1-3b cells. After 1 year, surviving mice were tested by real-time PCR for the presence of MRD.