Cytogenetic abnormalities in cells from patient IM-4 engrafted in NOD/SCID mice
Source . | Distribution, % . | Karyotypes . |
|---|---|---|
| IM BM (May 2002) | ||
| 25 | 45, XX, ins(1)(p13), add(3)(q11.2), del(5)(q15q33), − 10, − 12, add(16)(p11.2), − 17, + 2mar* | |
| 20 | 46, XX, der(6)t(1;6)(q25;p23) | |
| 55 | 46, XX | |
| Leukemic transformation BM (May 2003) | ||
| 80 | 45, XX, ?inv dup(1)(p21p33), der(3)t(3;16)(q11.2;p11.2), del(5)(q15q33), del(7)(q22), − 10, − 12, der(16)t(16;17)(p11.2;q11.2), − 17, + 2mar* | |
| 5 | 46, XX, der(6)t(1;6)(q25;p23) | |
| 15 | 46, XX | |
| Engrafted human cells in NOD/SCID mice (December 2003) | ||
| 13 | 45, XX, ?inv dup(1)(p21p33), der(3)t(3;16)(q11.2;p11.2), del(5)(q15q33), del(7)(q22), − 10, − 12, der(16)t(16;17)(p11.2;q11.2), − 17, + 2mar* | |
| 87 | 42≈44, XX, del(1)(p34.1), − 4, add(6)(p2?3), − 7, del(8)(q13), − 10, der(11)t(?4;11)(q27;q?23), add(12)(q34.3), add(13) (q34), − 17, ?dup(17)(p11.2), + mar |
Source . | Distribution, % . | Karyotypes . |
|---|---|---|
| IM BM (May 2002) | ||
| 25 | 45, XX, ins(1)(p13), add(3)(q11.2), del(5)(q15q33), − 10, − 12, add(16)(p11.2), − 17, + 2mar* | |
| 20 | 46, XX, der(6)t(1;6)(q25;p23) | |
| 55 | 46, XX | |
| Leukemic transformation BM (May 2003) | ||
| 80 | 45, XX, ?inv dup(1)(p21p33), der(3)t(3;16)(q11.2;p11.2), del(5)(q15q33), del(7)(q22), − 10, − 12, der(16)t(16;17)(p11.2;q11.2), − 17, + 2mar* | |
| 5 | 46, XX, der(6)t(1;6)(q25;p23) | |
| 15 | 46, XX | |
| Engrafted human cells in NOD/SCID mice (December 2003) | ||
| 13 | 45, XX, ?inv dup(1)(p21p33), der(3)t(3;16)(q11.2;p11.2), del(5)(q15q33), del(7)(q22), − 10, − 12, der(16)t(16;17)(p11.2;q11.2), − 17, + 2mar* | |
| 87 | 42≈44, XX, del(1)(p34.1), − 4, add(6)(p2?3), − 7, del(8)(q13), − 10, der(11)t(?4;11)(q27;q?23), add(12)(q34.3), add(13) (q34), − 17, ?dup(17)(p11.2), + mar |
Apparent differences between these karyotypes, other than the deletion 7, are the result of differences in interpretation between 2 cytogenetic laboratories; the chromosomes are in fact the same. The dates represent the time of sample collection.