Characteristics of patients with FA in the NAS and SLH cohorts
. | NAS . | SLH . | P† . |
|---|---|---|---|
| No. of cases | 145 | 117 | NA |
| Person-years of follow-up, total | 1983 | 508 | NA |
| Male-to-female ratio | 76:69 | 56:61 | .54 |
| Year of birth, (interquartile range*) | 1985 (1980-1990) | 1981 (1974-1987) | .003 |
| Median age, y at SCT (interquartile range) | 8.9 (5.7-12.7)‡ | 10.8 (7.4-13.5) | .048 |
| Total deaths prior to SCC | 21 | 48 | NA |
| Total SCC number§ | 7 | 11 | NA |
| Ages at onset of SCC, y | 23, 27, 28, 33, 33, 44, 44 | 10, 16, 17, 17, 18, 19, 22, 23, 24, 28, 33 | .004 |
| Time from transplantation to onset of SCC, y | NA | 5.5, 5.7, 7.5, 8.4, 7.0, 12.4, 9.5, 9.4, 13.8, 21.8, 14.4 | NA |
. | NAS . | SLH . | P† . |
|---|---|---|---|
| No. of cases | 145 | 117 | NA |
| Person-years of follow-up, total | 1983 | 508 | NA |
| Male-to-female ratio | 76:69 | 56:61 | .54 |
| Year of birth, (interquartile range*) | 1985 (1980-1990) | 1981 (1974-1987) | .003 |
| Median age, y at SCT (interquartile range) | 8.9 (5.7-12.7)‡ | 10.8 (7.4-13.5) | .048 |
| Total deaths prior to SCC | 21 | 48 | NA |
| Total SCC number§ | 7 | 11 | NA |
| Ages at onset of SCC, y | 23, 27, 28, 33, 33, 44, 44 | 10, 16, 17, 17, 18, 19, 22, 23, 24, 28, 33 | .004 |
| Time from transplantation to onset of SCC, y | NA | 5.5, 5.7, 7.5, 8.4, 7.0, 12.4, 9.5, 9.4, 13.8, 21.8, 14.4 | NA |
NA indicates not applicable.
The interquartile range includes the middle 50% of the data.
P value from Fisher exact test (male-to-female ratio) or Wilcoxon test (other contrasts).
Fifty subjects in NAS had a stem cell transplant (BMT); these subjects were not followed beyond BMT in this analysis.
These tumors (all head and neck cancers) arose before BMT in NAS and after BMT in SLH.