Median administered dose versus scheduled dose
. | Imatinib . | . | . | PegIFN . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | Administered . | . | . | Administered . | . | ||||
| Cohort . | Scheduled, mg/d . | Median, mg/d . | % . | Scheduled, μg/wk . | Median, μg/wk . | % . | ||||
| First | 400 | 360 | 90 | 50 | 36 | 72 | ||||
| Second | 400 | 350 | 87 | 100 | 35 | 35 | ||||
| Third | 400 | 310 | 77 | 150 | 32 | 21 | ||||
. | Imatinib . | . | . | PegIFN . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | Administered . | . | . | Administered . | . | ||||
| Cohort . | Scheduled, mg/d . | Median, mg/d . | % . | Scheduled, μg/wk . | Median, μg/wk . | % . | ||||
| First | 400 | 360 | 90 | 50 | 36 | 72 | ||||
| Second | 400 | 350 | 87 | 100 | 35 | 35 | ||||
| Third | 400 | 310 | 77 | 150 | 32 | 21 | ||||
The administered dose of IM was significantly lower (Student t test) in the third cohort than in the second cohort (P = .03) and the first cohort (P = .01).