Lymphocyte counts in WT, C2GIcNAcT-1−/−, and HEC-GIcNAc6ST−/− organs
. | Lymphocyte counts × 103 ± SEM . | . | . | ||
---|---|---|---|---|---|
. | WT . | C2−/− . | HEC-GIcNAc6ST−/− . | ||
PLN | |||||
Total | 11.98 ± 0.81 | 10.30 ± 1.46* | 6.68 ± 1.33† | ||
CD4+ | 5.58 ± 0.31 | 5.13 ± 0.74 | 3.87 ± 0.73* | ||
CD8+ | 3.56 ± 0.36 | 3.14 ± 0.55 | 1.96 ± 0.43* | ||
CD19+ | 2.47 ± 0.22 | 1.78 ± 0.20* | 0.47 ± 0.12‡ | ||
MLN | |||||
Total | 20.71 ± 2.74 | 24.52 ± 1.67 | 20.32 ± 1.30 | ||
CD4+ | 8.55 ± 1.03 | 9.74 ± 0.94 | 9.18 ± 0.33 | ||
CD8+ | 5.19 ± 0.89 | 6.27 ± 1.89 | 4.73 ± 0.16 | ||
CD19+ | 6.45 ± 0.99 | 8.48 ± 0.79 | 7.91 ± 1.98 | ||
PP | |||||
Total | 10.96 ± 0.85 | 9.76 ± 2.32 | 10.44 ± 4.20 | ||
CD4+ | 2.03 ± 0.28 | 1.62 ± 0.58 | 2.34 ± 1.13 | ||
CD8+ | 0.65 ± 0.16 | 0.77 ± 0.23 | 0.66 ± 0.30 | ||
CD19+ | 7.88 ± 0.70 | 6.65 ± 1.94 | 6.20 ± 1.75 |
. | Lymphocyte counts × 103 ± SEM . | . | . | ||
---|---|---|---|---|---|
. | WT . | C2−/− . | HEC-GIcNAc6ST−/− . | ||
PLN | |||||
Total | 11.98 ± 0.81 | 10.30 ± 1.46* | 6.68 ± 1.33† | ||
CD4+ | 5.58 ± 0.31 | 5.13 ± 0.74 | 3.87 ± 0.73* | ||
CD8+ | 3.56 ± 0.36 | 3.14 ± 0.55 | 1.96 ± 0.43* | ||
CD19+ | 2.47 ± 0.22 | 1.78 ± 0.20* | 0.47 ± 0.12‡ | ||
MLN | |||||
Total | 20.71 ± 2.74 | 24.52 ± 1.67 | 20.32 ± 1.30 | ||
CD4+ | 8.55 ± 1.03 | 9.74 ± 0.94 | 9.18 ± 0.33 | ||
CD8+ | 5.19 ± 0.89 | 6.27 ± 1.89 | 4.73 ± 0.16 | ||
CD19+ | 6.45 ± 0.99 | 8.48 ± 0.79 | 7.91 ± 1.98 | ||
PP | |||||
Total | 10.96 ± 0.85 | 9.76 ± 2.32 | 10.44 ± 4.20 | ||
CD4+ | 2.03 ± 0.28 | 1.62 ± 0.58 | 2.34 ± 1.13 | ||
CD8+ | 0.65 ± 0.16 | 0.77 ± 0.23 | 0.66 ± 0.30 | ||
CD19+ | 7.88 ± 0.70 | 6.65 ± 1.94 | 6.20 ± 1.75 |
*P <.05; †P <.01; ‡P <.001 versus WT (unpaired Student ttest).
WT, n = 7 mice; C2GIcNAcT-1−/−, n = 4 mice; HEC-GIcNAc6ST−/−, n = 3 mice.