Table 1.

FCs facilitate allogeneic HSC engraftment without acute GVHD


Engraftment

n

30-d survival, %

Donor chimerism at 3 mo, %

GVHD clinical score
Syngeneic HSC   6   100   -   1.0 ± 0.3  
Allogeneic HSC + TBM  10   10*  -   -  
Allogeneic HSC + FC
 
8
 
88.9
 
94.1 ± 1.8
 
1.25 ± 0.3
 

Engraftment

n

30-d survival, %

Donor chimerism at 3 mo, %

GVHD clinical score
Syngeneic HSC   6   100   -   1.0 ± 0.3  
Allogeneic HSC + TBM  10   10*  -   -  
Allogeneic HSC + FC
 
8
 
88.9
 
94.1 ± 1.8
 
1.25 ± 0.3
 
*

All HSC + TBM recipients died by 3 months

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