Table 3.

Comparison of imatinib uptake by CEM cells at 4°C and 37°C



Imatinib uptake, ng/million cells
Concentration, μM
4°C
37°C
0.5   4.0 (11)   10.5 (2.7)  
1   10.7 (2.1)   32.5 (6.4)* 
5   40.4 (2.9)   420.5 (70.2)* 
10   51.9 (6.7)   794.6 (159.5)* 
50   249.9 (54.3)   3156.1 (489.6) 
100
 
606.9 (108.8)
 
4243.0 (417.5)
 


Imatinib uptake, ng/million cells
Concentration, μM
4°C
37°C
0.5   4.0 (11)   10.5 (2.7)  
1   10.7 (2.1)   32.5 (6.4)* 
5   40.4 (2.9)   420.5 (70.2)* 
10   51.9 (6.7)   794.6 (159.5)* 
50   249.9 (54.3)   3156.1 (489.6) 
100
 
606.9 (108.8)
 
4243.0 (417.5)
 

Data are presented as mean (SEM) of 4 observations.

*

Significantly different from incubation at 4°C (P < .05)

Significantly different from incubation at 4°C (P < .005)

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