Comparison of leukocyte adhesion and change in ear thickness at 24 hours of CHS
Mouse . | Antibody treatment at antigen challenge . | Adhesion, cells/100 μm . | Change in ear thickness, cm-3 . |
|---|---|---|---|
| Wild-type | No treatment | 16 ± 2 | 15 ± 1.5 |
| Wild-type | Anti-P- and anti-E-selectin antibody | 0* | 0* |
| Wild-type | Anti-PSGL-1 antibody (4RA10) | 16 ± 0.6 | 13.3 ± 1.6 |
| PSGL-1-/- | No antibody | 17 ± 2.5 | 13 ± 1.3 |
| PSGL-1-/- | Anti-E-selectin antibody | 0* | 0* |
Mouse . | Antibody treatment at antigen challenge . | Adhesion, cells/100 μm . | Change in ear thickness, cm-3 . |
|---|---|---|---|
| Wild-type | No treatment | 16 ± 2 | 15 ± 1.5 |
| Wild-type | Anti-P- and anti-E-selectin antibody | 0* | 0* |
| Wild-type | Anti-PSGL-1 antibody (4RA10) | 16 ± 0.6 | 13.3 ± 1.6 |
| PSGL-1-/- | No antibody | 17 ± 2.5 | 13 ± 1.3 |
| PSGL-1-/- | Anti-E-selectin antibody | 0* | 0* |
Data are presented as mean ± SEM.
P < .05 relative to untreated value