Characteristics of treatment in patients with severe and moderate hemophilia given by age
. | 1972 . | 1978 . | 1985 . | 1992 . | 2001 . |
---|---|---|---|---|---|
Severe hemophilia | |||||
Prophylaxis, proportion of patients (%) | |||||
Children, 0-16 y | 22/65 (34) | 41/91 (45) | 69/111 (62) | 64/92 (70) | 112/130 (86) |
Adolescents, 17-25 y | 12/39 (31) | 27/54 (50) | 43/72 (60) | — | 38/42 (90) |
Adults, older than 25 y | 8/57 (14) | 28/99 (28) | 71/201 (35) | 119/232 (51) | 134/248 (54) |
Median age at first prophylaxis, y (range) | — | 8 (0-15) | 5 (1-15) | — | 2 (0-11) |
Home treatment, no. of patients (%) | 7 (4) | 72 (29) | 259 (67) | 286 (74) | 346 (82) |
Moderate hemophilia | |||||
Prophylaxis, proportion of patients (%) | |||||
Children, 0-16 y | 6/41 (15) | 9/41 (22) | 7/59 (12) | 7/41 (17) | 7/46 (15) |
Adolescents, 17-25 y | 4/14 (29) | 7/26 (27) | 1/19 (5) | — | 4/23 (17) |
Adults, older than 25 y | 1/27 (4) | 4/39 (10) | 10/97 (10) | 11/98 (11) | 10/107 (9) |
Home treatment, no. of patients (%) | 2 (2) | 14 (13) | 39 (22) | 51 (30) | 57 (32) |
. | 1972 . | 1978 . | 1985 . | 1992 . | 2001 . |
---|---|---|---|---|---|
Severe hemophilia | |||||
Prophylaxis, proportion of patients (%) | |||||
Children, 0-16 y | 22/65 (34) | 41/91 (45) | 69/111 (62) | 64/92 (70) | 112/130 (86) |
Adolescents, 17-25 y | 12/39 (31) | 27/54 (50) | 43/72 (60) | — | 38/42 (90) |
Adults, older than 25 y | 8/57 (14) | 28/99 (28) | 71/201 (35) | 119/232 (51) | 134/248 (54) |
Median age at first prophylaxis, y (range) | — | 8 (0-15) | 5 (1-15) | — | 2 (0-11) |
Home treatment, no. of patients (%) | 7 (4) | 72 (29) | 259 (67) | 286 (74) | 346 (82) |
Moderate hemophilia | |||||
Prophylaxis, proportion of patients (%) | |||||
Children, 0-16 y | 6/41 (15) | 9/41 (22) | 7/59 (12) | 7/41 (17) | 7/46 (15) |
Adolescents, 17-25 y | 4/14 (29) | 7/26 (27) | 1/19 (5) | — | 4/23 (17) |
Adults, older than 25 y | 1/27 (4) | 4/39 (10) | 10/97 (10) | 11/98 (11) | 10/107 (9) |
Home treatment, no. of patients (%) | 2 (2) | 14 (13) | 39 (22) | 51 (30) | 57 (32) |
—indicates not available.