Table 2.

Characteristics of treatment in patients with severe and moderate hemophilia given by age




1972

1978

1985

1992

2001
Severe hemophilia      
    Prophylaxis, proportion of patients (%)       
        Children, 0-16 y   22/65 (34)   41/91 (45)   69/111 (62)   64/92 (70)   112/130 (86)  
        Adolescents, 17-25 y   12/39 (31)   27/54 (50)   43/72 (60)   —   38/42 (90)  
        Adults, older than 25 y   8/57 (14)   28/99 (28)   71/201 (35)   119/232 (51)   134/248 (54)  
    Median age at first prophylaxis, y (range)   —   8 (0-15)   5 (1-15)   —   2 (0-11)  
    Home treatment, no. of patients (%)   7 (4)   72 (29)   259 (67)   286 (74)   346 (82)  
Moderate hemophilia      
    Prophylaxis, proportion of patients (%)       
        Children, 0-16 y   6/41 (15)   9/41 (22)   7/59 (12)   7/41 (17)   7/46 (15)  
        Adolescents, 17-25 y   4/14 (29)   7/26 (27)   1/19 (5)   —   4/23 (17)  
        Adults, older than 25 y   1/27 (4)   4/39 (10)   10/97 (10)   11/98 (11)   10/107 (9)  
    Home treatment, no. of patients (%)
 
2 (2)
 
14 (13)
 
39 (22)
 
51 (30)
 
57 (32)
 



1972

1978

1985

1992

2001
Severe hemophilia      
    Prophylaxis, proportion of patients (%)       
        Children, 0-16 y   22/65 (34)   41/91 (45)   69/111 (62)   64/92 (70)   112/130 (86)  
        Adolescents, 17-25 y   12/39 (31)   27/54 (50)   43/72 (60)   —   38/42 (90)  
        Adults, older than 25 y   8/57 (14)   28/99 (28)   71/201 (35)   119/232 (51)   134/248 (54)  
    Median age at first prophylaxis, y (range)   —   8 (0-15)   5 (1-15)   —   2 (0-11)  
    Home treatment, no. of patients (%)   7 (4)   72 (29)   259 (67)   286 (74)   346 (82)  
Moderate hemophilia      
    Prophylaxis, proportion of patients (%)       
        Children, 0-16 y   6/41 (15)   9/41 (22)   7/59 (12)   7/41 (17)   7/46 (15)  
        Adolescents, 17-25 y   4/14 (29)   7/26 (27)   1/19 (5)   —   4/23 (17)  
        Adults, older than 25 y   1/27 (4)   4/39 (10)   10/97 (10)   11/98 (11)   10/107 (9)  
    Home treatment, no. of patients (%)
 
2 (2)
 
14 (13)
 
39 (22)
 
51 (30)
 
57 (32)
 

—indicates not available.