Hematologic parameters and genotype in HbAS and beta-thal trait subjects
Subject no. . | Sex . | Age, y . | Hb, g/dL . | MCV, fL . | MCH, pg . | Genotype . | HbA2, % . | HbF, % . |
|---|---|---|---|---|---|---|---|---|
| HbAS subjects | ||||||||
| 1 | F | 27 | 13.2 | 81.3 | 26.6 | Codon 6 (A>T)/N | 2.5 | 1.2 |
| 2 | F | 22 | 14.0 | 86.1 | 30.2 | Codon 6 (A>T)/N | 2.4 | 0.5 |
| 3 | M | 28 | 15.2 | 91.5 | 31.4 | Codon 6 (A>T)/N | 2.9 | 1.0 |
| 4 | F | 20 | 12.7 | 77.1 | 28.9 | Codon 6 (A>T)/N | 2.3 | 1.1 |
| 5 | M | 34 | 14.4 | 82.4 | 29.1 | Codon 6 (A>T)/N | 2.5 | 1.1 |
| 6 | F | 29 | 13.3 | 76.3 | 26.2 | Codon 6 (A>T)/N | 1.9 | 1.6 |
| 7 | F | 25 | 14.1 | 84.8 | 28.8 | Codon 6 (A>T)/N | 2.4 | 0.7 |
| 8 | M | 27 | 14.9 | 80.9 | 30.1 | Codon 6 (A>T)/N | 2.8 | 0.6 |
| 9 | M | 31 | 13.6 | 83.4 | 27.7 | Codon 6 (A>T)/N | 2.6 | 1.1 |
| 10 | F | 31 | 13.1 | 78.5 | 26.6 | Codon 6 (A>T)/N | 2.4 | 1.2 |
| 11 | F | 28 | 12.6 | 81.0 | 25.5 | Codon 6 (A>T)/N | 2.2 | 1.3 |
| Beta thal trait subjects | ||||||||
| 1 | F | 23 | 10.6 | 63.6 | 18.5 | Codon 39 (C>T)/N | 4.6 | 0.7 |
| 2 | M | 28 | 12.4 | 68.5 | 20.3 | Codon 39 (C>T)/N | 4.7 | 0.0 |
| 3 | F | 40 | 10.6 | 63.8 | 18.8 | Codon 39 (C>T)/N | 5.4 | 2.3 |
| 4 | M | 39 | 12.5 | 63.0 | 21.0 | Codon 39 (C>T)/N | 5.0 | 2.6 |
| 5 | F | 41 | 11.4 | 61.0 | 20.3 | Codon 39 (C>T)/N | 5.8 | 0.5 |
| 6 | M | 48 | 12.1 | 64.0 | 18.6 | Codon 39 (C>T)/N | 5.7 | 0.0 |
| 7 | M | 51 | 14.3 | 62.5 | 20.8 | Codon 39 (C>T)/N | 6.0 | 0.6 |
| 8 | F | 58 | 10.6 | 69.0 | 20.7 | Codon 39 (C>T)/N | 5.5 | 2.7 |
| 9 | F | 35 | 12.3 | 67.0 | 21.2 | Codon 39 (C>T)/N | 4.9 | 3.0 |
| 10 | F | 51 | 12.9 | 73.0 | 21.4 | Codon 39 (C>T)/N | 5.1 | 1.2 |
| 11 | F | 35 | 10.4 | 59.8 | 18.9 | Codon 39 (C>T)/N | 6.0 | 1.1 |
| 12 | F | 31 | 11.1 | 61.7 | 19.6 | Codon 39 (C>T)/N | 5.6 | 0.9 |
Subject no. . | Sex . | Age, y . | Hb, g/dL . | MCV, fL . | MCH, pg . | Genotype . | HbA2, % . | HbF, % . |
|---|---|---|---|---|---|---|---|---|
| HbAS subjects | ||||||||
| 1 | F | 27 | 13.2 | 81.3 | 26.6 | Codon 6 (A>T)/N | 2.5 | 1.2 |
| 2 | F | 22 | 14.0 | 86.1 | 30.2 | Codon 6 (A>T)/N | 2.4 | 0.5 |
| 3 | M | 28 | 15.2 | 91.5 | 31.4 | Codon 6 (A>T)/N | 2.9 | 1.0 |
| 4 | F | 20 | 12.7 | 77.1 | 28.9 | Codon 6 (A>T)/N | 2.3 | 1.1 |
| 5 | M | 34 | 14.4 | 82.4 | 29.1 | Codon 6 (A>T)/N | 2.5 | 1.1 |
| 6 | F | 29 | 13.3 | 76.3 | 26.2 | Codon 6 (A>T)/N | 1.9 | 1.6 |
| 7 | F | 25 | 14.1 | 84.8 | 28.8 | Codon 6 (A>T)/N | 2.4 | 0.7 |
| 8 | M | 27 | 14.9 | 80.9 | 30.1 | Codon 6 (A>T)/N | 2.8 | 0.6 |
| 9 | M | 31 | 13.6 | 83.4 | 27.7 | Codon 6 (A>T)/N | 2.6 | 1.1 |
| 10 | F | 31 | 13.1 | 78.5 | 26.6 | Codon 6 (A>T)/N | 2.4 | 1.2 |
| 11 | F | 28 | 12.6 | 81.0 | 25.5 | Codon 6 (A>T)/N | 2.2 | 1.3 |
| Beta thal trait subjects | ||||||||
| 1 | F | 23 | 10.6 | 63.6 | 18.5 | Codon 39 (C>T)/N | 4.6 | 0.7 |
| 2 | M | 28 | 12.4 | 68.5 | 20.3 | Codon 39 (C>T)/N | 4.7 | 0.0 |
| 3 | F | 40 | 10.6 | 63.8 | 18.8 | Codon 39 (C>T)/N | 5.4 | 2.3 |
| 4 | M | 39 | 12.5 | 63.0 | 21.0 | Codon 39 (C>T)/N | 5.0 | 2.6 |
| 5 | F | 41 | 11.4 | 61.0 | 20.3 | Codon 39 (C>T)/N | 5.8 | 0.5 |
| 6 | M | 48 | 12.1 | 64.0 | 18.6 | Codon 39 (C>T)/N | 5.7 | 0.0 |
| 7 | M | 51 | 14.3 | 62.5 | 20.8 | Codon 39 (C>T)/N | 6.0 | 0.6 |
| 8 | F | 58 | 10.6 | 69.0 | 20.7 | Codon 39 (C>T)/N | 5.5 | 2.7 |
| 9 | F | 35 | 12.3 | 67.0 | 21.2 | Codon 39 (C>T)/N | 4.9 | 3.0 |
| 10 | F | 51 | 12.9 | 73.0 | 21.4 | Codon 39 (C>T)/N | 5.1 | 1.2 |
| 11 | F | 35 | 10.4 | 59.8 | 18.9 | Codon 39 (C>T)/N | 6.0 | 1.1 |
| 12 | F | 31 | 11.1 | 61.7 | 19.6 | Codon 39 (C>T)/N | 5.6 | 0.9 |
MCV indicates mean corpuscular volume; MCH, mean corpuscular hemoglobin.