Gene usage in the 7 groups with restricted HCDR3 features identified by amino acid sequence alignment
VH gene . | No. of cases with restricted HCDR3 features . | D gene . | JH gene . | VL gene (no. cases with indicated VL gene/total no. cases) . |
|---|---|---|---|---|
| VH3-21 | 22 | — | JH6 | λ2-14 (19/22) |
| VH1-69 | 4 | D3-16 | JH3 | κA27 (4/4) |
| VH1-69 | 3 | D3-3 | JH6 | λ2-6 (2/3*) |
| VH1-2 | 5 | D1-26 | JH6 | κB3 (3/5*) |
| VH1-3 | 9 | D6-19 | JH4 | κO2 (9/9) |
| VH1-18 | 3 | D6-19/D3-22 | JH4 | κO2 (3/3) |
| VH4-39 | 5 | D6-13/D6-19 | JH5 | κO2 (4/5) |
VH gene . | No. of cases with restricted HCDR3 features . | D gene . | JH gene . | VL gene (no. cases with indicated VL gene/total no. cases) . |
|---|---|---|---|---|
| VH3-21 | 22 | — | JH6 | λ2-14 (19/22) |
| VH1-69 | 4 | D3-16 | JH3 | κA27 (4/4) |
| VH1-69 | 3 | D3-3 | JH6 | λ2-6 (2/3*) |
| VH1-2 | 5 | D1-26 | JH6 | κB3 (3/5*) |
| VH1-3 | 9 | D6-19 | JH4 | κO2 (9/9) |
| VH1-18 | 3 | D6-19/D3-22 | JH4 | κO2 (3/3) |
| VH4-39 | 5 | D6-13/D6-19 | JH5 | κO2 (4/5) |
— indicates no D gene identified.
The VL gene usage was not determined in one case