Most frequent VH genes used in this cohort of 346 CLL cases
VH gene . | Total no. (%) . | Unmutated VH genes . | Mutated VH genes . |
|---|---|---|---|
| VH1-69 | 58 (14) | 54 | 4 |
| VH3-21 | 35 (9) | 11 | 24 |
| VH4-34 | 28 (7) | 11 | 17 |
| VH3-30 | 23 (6) | 11 | 12 |
| VH3-23 | 21 (5) | 3 | 18 |
| Vh1-2 | 17 (4) | 12 | 5 |
| VH4-39 | 16 (4) | 13 | 3 |
| VH3-7 | 14 (3) | 2 | 12 |
| VH3-9 | 13 (3) | 9 | 4 |
| VH3-33 | 13 (3) | 9 | 4 |
| Other VH genes | 169 (42*) | 100 | 69 |
| Total | 407 (100) | 235 | 172 |
VH gene . | Total no. (%) . | Unmutated VH genes . | Mutated VH genes . |
|---|---|---|---|
| VH1-69 | 58 (14) | 54 | 4 |
| VH3-21 | 35 (9) | 11 | 24 |
| VH4-34 | 28 (7) | 11 | 17 |
| VH3-30 | 23 (6) | 11 | 12 |
| VH3-23 | 21 (5) | 3 | 18 |
| Vh1-2 | 17 (4) | 12 | 5 |
| VH4-39 | 16 (4) | 13 | 3 |
| VH3-7 | 14 (3) | 2 | 12 |
| VH3-9 | 13 (3) | 9 | 4 |
| VH3-33 | 13 (3) | 9 | 4 |
| Other VH genes | 169 (42*) | 100 | 69 |
| Total | 407 (100) | 235 | 172 |
VH1-3, 3%; VH1-18, 2.5%; and VH1-46, 1.2%