Hematologic and clinical features of patients with hypodiploidy with 30 to 39 chromosomes and near-triploidy
. | Hypodiploidy 30-39 chromosomes . | Near-triploidy . |
---|---|---|
No. patients | 11 | 13 |
Median age, y (range) | 46 (15-73) | 52 (21-73) |
Sex, no. male/no. female | 5/6 | 8/5 |
Median hemoglobin level, g/L | 97 | 99 |
Median WBC count, × 109/L (range) | 4.5 (1.6-7.4) | 4.2 (0.9-32.3) |
Median platelet count, × 109/L | 55 | 45 |
Immunophenotype* | B lineage | B lineage |
CD19+CD10-CD20-, % (no. patients) | 27 (3) | 16.6 (2) |
CD19+CD10+CD20+, % (no. patients) | 73 (8) | 83.3 (10) |
CR rates, %† | 70 | 46 |
OS, mos. | 11.1 | 8.1 |
Median DFS, mos. | 5 | 18.2 |
. | Hypodiploidy 30-39 chromosomes . | Near-triploidy . |
---|---|---|
No. patients | 11 | 13 |
Median age, y (range) | 46 (15-73) | 52 (21-73) |
Sex, no. male/no. female | 5/6 | 8/5 |
Median hemoglobin level, g/L | 97 | 99 |
Median WBC count, × 109/L (range) | 4.5 (1.6-7.4) | 4.2 (0.9-32.3) |
Median platelet count, × 109/L | 55 | 45 |
Immunophenotype* | B lineage | B lineage |
CD19+CD10-CD20-, % (no. patients) | 27 (3) | 16.6 (2) |
CD19+CD10+CD20+, % (no. patients) | 73 (8) | 83.3 (10) |
CR rates, %† | 70 | 46 |
OS, mos. | 11.1 | 8.1 |
Median DFS, mos. | 5 | 18.2 |