Expression of different effector molecules in circulating and IVS immunization-induced CD8+, tHLA+ T cells
. | Granzyme-A . | Perforin . | CD11a . | CD2 . |
---|---|---|---|---|
Ex vivo | ||||
P10 | 9.78 | 42.02 | 383.22 | 224.70 |
P11 | 2.24 | 46.84 | 221.78 | 169.61 |
P2 | 1.19 | 17.61 | 243.28 | 176.77 |
Average | 4.40 | 35.49 | 282.76 | 190.36 |
SEM | 3.35 | 11.19 | 62.62 | 21.40 |
After IVS | ||||
P10 | 40.08 | 78.09 | 730.74 | 928.16 |
P11 | 29.59 | 88.75 | 780.26 | 585.61 |
P2 | 55.43 | 51.18 | 871.61 | 462.50 |
Average | 41.70 | 72.67 | 794.20 | 658.76 |
SEM | 9.28 | 13.83 | 51.04 | 172.35 |
Paired t test P | .024 | .002 | .013 | .031 |
. | Granzyme-A . | Perforin . | CD11a . | CD2 . |
---|---|---|---|---|
Ex vivo | ||||
P10 | 9.78 | 42.02 | 383.22 | 224.70 |
P11 | 2.24 | 46.84 | 221.78 | 169.61 |
P2 | 1.19 | 17.61 | 243.28 | 176.77 |
Average | 4.40 | 35.49 | 282.76 | 190.36 |
SEM | 3.35 | 11.19 | 62.62 | 21.40 |
After IVS | ||||
P10 | 40.08 | 78.09 | 730.74 | 928.16 |
P11 | 29.59 | 88.75 | 780.26 | 585.61 |
P2 | 55.43 | 51.18 | 871.61 | 462.50 |
Average | 41.70 | 72.67 | 794.20 | 658.76 |
SEM | 9.28 | 13.83 | 51.04 | 172.35 |
Paired t test P | .024 | .002 | .013 | .031 |
Data are presented as mean fluorescence intensity after subtraction of background fluorescence (fluorescence of isotype-matched control samples).