Pancytopenia and marrow aplasia
Treatment . | No. . | WBCs 106/mL . | RBCs 109/mL . | Hemoglobin level, g/dL . | Platelets, 106/mL . | BM cells, 106 . |
|---|---|---|---|---|---|---|
| Experiment 1 | ||||||
| Untreated | 2 | 8.4 ± 1.0 | 8.1 ± 0.2 | — | — | 286 ± 4 |
| TBI only | 5 | 3.4 ± 0.6 | 8.2 ± 0.2 | — | — | 168 ± 9 |
| TBI + B6 LN cells | 5 | 0.9 ± 0.1 | 3.2 ± 0.9 | — | — | 25 ± 4 |
| Experiment 3 | ||||||
| Untreated | 2 | 8.8 ± 1.2 | 8.5 ± 0.4 | — | — | — |
| TBI only | 5 | 3.6 ± 0.3 | 7.7 ± 0.1 | — | — | — |
| TBI + B6 LN cells | 8 | 0.7 ± 0.1 | 2.8 ± 0.4 | — | — | — |
| Experiment 4 | ||||||
| Untreated | 4 | 9.5 ± 0.4 | 9.6 ± 0.2 | 16.2 ± 0.8 | 758 ± 14 | 277 ± 14 |
| TBI only | 5 | 3.2 ± 0.5 | 8.1 ± 0.3 | 13.6 ± 0.8 | 446 ± 42 | 151 ± 2 |
| TBI + B6 LN cells | 2 | 0.8 ± 0.7 | 1.3 ± 0.2 | 2.0 ± 0.2 | 90 ± 71 | 11 ± 2 |
| TBI + BA-LN cells | 5 | 0.6 ± 0.2 | 6.6 ± 0.3 | 9.8 ± 0.5 | 110 ± 26 | 27 ± 1 |
Treatment . | No. . | WBCs 106/mL . | RBCs 109/mL . | Hemoglobin level, g/dL . | Platelets, 106/mL . | BM cells, 106 . |
|---|---|---|---|---|---|---|
| Experiment 1 | ||||||
| Untreated | 2 | 8.4 ± 1.0 | 8.1 ± 0.2 | — | — | 286 ± 4 |
| TBI only | 5 | 3.4 ± 0.6 | 8.2 ± 0.2 | — | — | 168 ± 9 |
| TBI + B6 LN cells | 5 | 0.9 ± 0.1 | 3.2 ± 0.9 | — | — | 25 ± 4 |
| Experiment 3 | ||||||
| Untreated | 2 | 8.8 ± 1.2 | 8.5 ± 0.4 | — | — | — |
| TBI only | 5 | 3.6 ± 0.3 | 7.7 ± 0.1 | — | — | — |
| TBI + B6 LN cells | 8 | 0.7 ± 0.1 | 2.8 ± 0.4 | — | — | — |
| Experiment 4 | ||||||
| Untreated | 4 | 9.5 ± 0.4 | 9.6 ± 0.2 | 16.2 ± 0.8 | 758 ± 14 | 277 ± 14 |
| TBI only | 5 | 3.2 ± 0.5 | 8.1 ± 0.3 | 13.6 ± 0.8 | 446 ± 42 | 151 ± 2 |
| TBI + B6 LN cells | 2 | 0.8 ± 0.7 | 1.3 ± 0.2 | 2.0 ± 0.2 | 90 ± 71 | 11 ± 2 |
| TBI + BA-LN cells | 5 | 0.6 ± 0.2 | 6.6 ± 0.3 | 9.8 ± 0.5 | 110 ± 26 | 27 ± 1 |
Untreated mice received no treatment at all. TBI-only mice received 5 Gy TBI but no LN cells. BM cells in all experiments and RBCs and WBCs in experiments 1 and 3 were counted on a Z2 Coulter Counter. CBCs were performed in experiments 4 using a Hemavet analyzer. Data presented are means ± standard error.