Mean changes from baseline for lumber spine BMC and BMD
Follow-up interval . | ALN . | Placebo . | P . |
|---|---|---|---|
| 6 mo | |||
| ΔBMC, g | 3.97 ± 5.26 | 0.02 ± 1.83 | .0168 |
| ΔBMD, g/cm2 | 0.0349 ± 0.0228 | 0.0052 ± 0.0208 | .0013 |
| 12 mo | |||
| ΔBMC, g | 4.33 ± 3.18 | -0.13 ± 2.53 | .0012 |
| ΔBMD, g/cm2 | 0.0592 ± 0.0427 | 0.0085 ± 0.0373 | .0062 |
| 18 mo | |||
| ΔBMC, g | 6.40 ± 1.77 | -0.52 ± 1.36 | .0004 |
| ΔBMD, g/cm2 | 0.0679 ± 0.0207 | 0.015 ± 0.0343 | .0236 |
| 24 mo | |||
| ΔBMC, g | 6.62 ± 2.01 | -0.87 ± 1.68 | .0110 |
| ΔBMD, g/cm2 | 0.0726 ± 0.0187 | -0.006 ± 0.005 | .0053 |
Follow-up interval . | ALN . | Placebo . | P . |
|---|---|---|---|
| 6 mo | |||
| ΔBMC, g | 3.97 ± 5.26 | 0.02 ± 1.83 | .0168 |
| ΔBMD, g/cm2 | 0.0349 ± 0.0228 | 0.0052 ± 0.0208 | .0013 |
| 12 mo | |||
| ΔBMC, g | 4.33 ± 3.18 | -0.13 ± 2.53 | .0012 |
| ΔBMD, g/cm2 | 0.0592 ± 0.0427 | 0.0085 ± 0.0373 | .0062 |
| 18 mo | |||
| ΔBMC, g | 6.40 ± 1.77 | -0.52 ± 1.36 | .0004 |
| ΔBMD, g/cm2 | 0.0679 ± 0.0207 | 0.015 ± 0.0343 | .0236 |
| 24 mo | |||
| ΔBMC, g | 6.62 ± 2.01 | -0.87 ± 1.68 | .0110 |
| ΔBMD, g/cm2 | 0.0726 ± 0.0187 | -0.006 ± 0.005 | .0053 |
Values for ALN and placebo represent the mean ± the standard error of the mean.