Side effects according to treatment arms
Effects . | CHOP-21, % . | CHOP-14, % . | CHOEP-21, % . | CHOEP-14, % . | P . |
|---|---|---|---|---|---|
| Leukocytopenia | 34.1 | 33.6 | 73.6 | 72.5 | < .001 |
| Thrombocytopenia | 2.4 | 1.2 | 7.0 | 22.2 | < .001 |
| Anemia | 3.6 | 5.6 | 8.5 | 35.4 | < .001 |
| Infection | 1.8 | 4.2 | 4.4 | 5.2 | .390 |
| Mucositis | 2.9 | 3.0 | 1.6 | 6.9 | .048 |
| Cardiac toxicity | 0.6 | 0.6 | 2.8 | 0.6 | .232 |
| Neurologic toxicity | 3.5 | 0.6 | 1.6 | 3.5 | .171 |
| Renal toxicity | 0.0 | 0.0 | 0.0 | 1.2 | .182 |
| Lung toxicity | 0.0 | 0.6 | 1.7 | 1.7 | .320 |
| Nausea or vomiting | 11.7 | 6.5 | 9.4 | 8.6 | .415 |
| Alopecia | 63.6 | 64.8 | 70.9 | 67.6 | .469 |
Effects . | CHOP-21, % . | CHOP-14, % . | CHOEP-21, % . | CHOEP-14, % . | P . |
|---|---|---|---|---|---|
| Leukocytopenia | 34.1 | 33.6 | 73.6 | 72.5 | < .001 |
| Thrombocytopenia | 2.4 | 1.2 | 7.0 | 22.2 | < .001 |
| Anemia | 3.6 | 5.6 | 8.5 | 35.4 | < .001 |
| Infection | 1.8 | 4.2 | 4.4 | 5.2 | .390 |
| Mucositis | 2.9 | 3.0 | 1.6 | 6.9 | .048 |
| Cardiac toxicity | 0.6 | 0.6 | 2.8 | 0.6 | .232 |
| Neurologic toxicity | 3.5 | 0.6 | 1.6 | 3.5 | .171 |
| Renal toxicity | 0.0 | 0.0 | 0.0 | 1.2 | .182 |
| Lung toxicity | 0.0 | 0.6 | 1.7 | 1.7 | .320 |
| Nausea or vomiting | 11.7 | 6.5 | 9.4 | 8.6 | .415 |
| Alopecia | 63.6 | 64.8 | 70.9 | 67.6 | .469 |
Values in the table represent the percentage of all patients experiencing the respective side effect at least once.