Genes up-regulated more than 4-fold in SDF versus FDF
Gene . | Symbol . | Accession no. . | Ratio (Log2) . | SD . |
---|---|---|---|---|
Cell surface receptors/ligands | ||||
HLA-DR α heavy-chain a class II antigen (MHC)* | HLA-DRA | H78841 | 2.5 | 0.8 |
Peripheral lymph node homing receptor homolog* | SELL | H00662 | 3.3 | 1.3 |
MHC class II dr β* | HLA-DRB1,5 | H90289 | 2.0 | 0.9 |
CD133 antigen† | PROML1 | R40057 | 3.7 | 0.8 |
m130 antigen cytoplasmic variant 2* | CD163 | N73867 | 3.2 | 1.7 |
HLA-DP-β 1 gene and HLA-DP-α-1 gene exon 1‡ | HLA-DPB1 | AA496472 | 2.2 | 0.7 |
Complement component 1, q subcomponent, receptor 1* | CIQR1 | H28298 | 2.1 | 1.6 |
Human platelet endothelial cell adhesion molecule‡ | PECAM1 | R22412 | 2.2 | 0.6 |
Low-affinity IgG receptor CD16 (fcgriii)* | FCGR3A | N47495 | 2.7 | 1.4 |
Toll/IL-1 receptor-like protein 4 (til4) | TLR2 | AA004805 | 2.1 | 1.6 |
Mannose receptor, c type 1* | MRC1 | AA043388 | 2.2 | 1.0 |
HLA-SB(dp) α gene* | HLA-DPA1 | H38801 | 2.0 | 0.5 |
Transporter/signal transduction | ||||
Multidrug resistance gene 1 (MDR1)‡ | ABCB1 | AA135957 | 2.1 | 0.5 |
Soluble guanylate cyclase small subunit* | GUCY1B3 | W73155 | 2.0 | 1.4 |
Glucose transport-like 5 (glut5)* | SLC2A5 | AA459707 | 2.0 | 1.4 |
Osteopontin* | SPP1 | R59298 | 3.0 | 1.8 |
Interferon γ—induced protein* | IFI16 | AA126928 | 2.0 | 1.0 |
Prepromultimerin | MMRN | AA423867 | 2.1 | 1.4 |
kiaa0337 gene* | KIAA0337 | AA236696 | 2.0 | 0.7 |
Transcription factors/cell cycle | ||||
v-ets erythroblastosis virus e26 oncogene-like (avian)‡ | ERG | R01192 | 2.9 | 0.9 |
erg2 gene† | ERG | R87572 | 2.9 | 0.4 |
cyclin G2* | CCNG2 | H18981 | 2.0 | 0.8 |
Cellular component/cytoskeleton | ||||
Fibronectin (fn precursor) | FN1 | W57892 | 2.1 | 1.4 |
Dermal fibroblast elastin‡ | WDR1 | R49766 | 2.2 | 0.6 |
Other/unknown | ||||
Williams-Beuren syndrome chromosome region 5‡ | WBSCR5 | AF086239 | 2.1 | 0.6 |
kiaa 1766 protein | KIAA1766 | AI800340 | 2.1 | 1.6 |
kiaa0125 gene product‡ | KIAA0125 | H65343 | 2.2 | 0.6 |
Melanoma-associated gene‡ | D2S448 | R09509 | 2.0 | 0.5 |
lim protein slimmer* | FHL1 | AA134667 | 2.3 | 1.1 |
kiaa0581 protein‡ | PLCB1 | AA011027 | 2.2 | 0.8 |
ralgds-like gene | RGL | AA013091 | 2.1 | 1.9 |
Cysteine and tyrosine-rich 1* | CYYR1 | AA125921 | 2.0 | 0.8 |
Hypothetical protein flj14054‡ | FLJ14054 | H68441 | 2.9 | 0.8 |
cDNA dkfzp586e1624* | AA042839 | 2.3 | 0.8 | |
Acyl-protein thioesterase | LYPLA2 | R38687 | 2.3 | 3.3 |
Hypothetical protein flj10628‡ | FLJ10628 | AA400002 | 2.3 | 0.7 |
Gene . | Symbol . | Accession no. . | Ratio (Log2) . | SD . |
---|---|---|---|---|
Cell surface receptors/ligands | ||||
HLA-DR α heavy-chain a class II antigen (MHC)* | HLA-DRA | H78841 | 2.5 | 0.8 |
Peripheral lymph node homing receptor homolog* | SELL | H00662 | 3.3 | 1.3 |
MHC class II dr β* | HLA-DRB1,5 | H90289 | 2.0 | 0.9 |
CD133 antigen† | PROML1 | R40057 | 3.7 | 0.8 |
m130 antigen cytoplasmic variant 2* | CD163 | N73867 | 3.2 | 1.7 |
HLA-DP-β 1 gene and HLA-DP-α-1 gene exon 1‡ | HLA-DPB1 | AA496472 | 2.2 | 0.7 |
Complement component 1, q subcomponent, receptor 1* | CIQR1 | H28298 | 2.1 | 1.6 |
Human platelet endothelial cell adhesion molecule‡ | PECAM1 | R22412 | 2.2 | 0.6 |
Low-affinity IgG receptor CD16 (fcgriii)* | FCGR3A | N47495 | 2.7 | 1.4 |
Toll/IL-1 receptor-like protein 4 (til4) | TLR2 | AA004805 | 2.1 | 1.6 |
Mannose receptor, c type 1* | MRC1 | AA043388 | 2.2 | 1.0 |
HLA-SB(dp) α gene* | HLA-DPA1 | H38801 | 2.0 | 0.5 |
Transporter/signal transduction | ||||
Multidrug resistance gene 1 (MDR1)‡ | ABCB1 | AA135957 | 2.1 | 0.5 |
Soluble guanylate cyclase small subunit* | GUCY1B3 | W73155 | 2.0 | 1.4 |
Glucose transport-like 5 (glut5)* | SLC2A5 | AA459707 | 2.0 | 1.4 |
Osteopontin* | SPP1 | R59298 | 3.0 | 1.8 |
Interferon γ—induced protein* | IFI16 | AA126928 | 2.0 | 1.0 |
Prepromultimerin | MMRN | AA423867 | 2.1 | 1.4 |
kiaa0337 gene* | KIAA0337 | AA236696 | 2.0 | 0.7 |
Transcription factors/cell cycle | ||||
v-ets erythroblastosis virus e26 oncogene-like (avian)‡ | ERG | R01192 | 2.9 | 0.9 |
erg2 gene† | ERG | R87572 | 2.9 | 0.4 |
cyclin G2* | CCNG2 | H18981 | 2.0 | 0.8 |
Cellular component/cytoskeleton | ||||
Fibronectin (fn precursor) | FN1 | W57892 | 2.1 | 1.4 |
Dermal fibroblast elastin‡ | WDR1 | R49766 | 2.2 | 0.6 |
Other/unknown | ||||
Williams-Beuren syndrome chromosome region 5‡ | WBSCR5 | AF086239 | 2.1 | 0.6 |
kiaa 1766 protein | KIAA1766 | AI800340 | 2.1 | 1.6 |
kiaa0125 gene product‡ | KIAA0125 | H65343 | 2.2 | 0.6 |
Melanoma-associated gene‡ | D2S448 | R09509 | 2.0 | 0.5 |
lim protein slimmer* | FHL1 | AA134667 | 2.3 | 1.1 |
kiaa0581 protein‡ | PLCB1 | AA011027 | 2.2 | 0.8 |
ralgds-like gene | RGL | AA013091 | 2.1 | 1.9 |
Cysteine and tyrosine-rich 1* | CYYR1 | AA125921 | 2.0 | 0.8 |
Hypothetical protein flj14054‡ | FLJ14054 | H68441 | 2.9 | 0.8 |
cDNA dkfzp586e1624* | AA042839 | 2.3 | 0.8 | |
Acyl-protein thioesterase | LYPLA2 | R38687 | 2.3 | 3.3 |
Hypothetical protein flj10628‡ | FLJ10628 | AA400002 | 2.3 | 0.7 |
The Log2 ratios of SDF/FDF were the average values of 6 hybridizations in 3 experiments. Error estimate is given as SD. Probability of differential gene expression in relation to all high- quality signals was determined with the Student t test. MHC indicates major histocompatibility complex. Accession numbers from GenBank are provided.
P < .01.
P < .0001.
P < .001.