Table 3.

Genes up-regulated more than 4-fold in SDF versus FDF


Gene

Symbol

Accession no.

Ratio (Log2)

SD
Cell surface receptors/ligands     
    HLA-DR α heavy-chain a class II antigen (MHC)* HLA-DRA H78841  2.5   0.8  
    Peripheral lymph node homing receptor homolog* SELL H00662  3.3   1.3  
    MHC class II dr β* HLA-DRB1,5 H90289  2.0   0.9  
    CD133 antigen PROML1 R40057  3.7   0.8  
    m130 antigen cytoplasmic variant 2* CD163 N73867  3.2   1.7  
    HLA-DP-β 1 gene and HLA-DP-α-1 gene exon 1 HLA-DPB1 AA496472  2.2   0.7  
    Complement component 1, q subcomponent, receptor 1* CIQR1 H28298  2.1   1.6  
    Human platelet endothelial cell adhesion molecule PECAM1 R22412  2.2   0.6  
    Low-affinity IgG receptor CD16 (fcgriii)* FCGR3A N47495  2.7   1.4  
    Toll/IL-1 receptor-like protein 4 (til4)  TLR2 AA004805  2.1   1.6  
    Mannose receptor, c type 1* MRC1 AA043388  2.2   1.0  
    HLA-SB(dp) α gene* HLA-DPA1 H38801  2.0   0.5  
Transporter/signal transduction     
    Multidrug resistance gene 1 (MDR1) ABCB1 AA135957  2.1   0.5  
    Soluble guanylate cyclase small subunit* GUCY1B3 W73155  2.0   1.4  
    Glucose transport-like 5 (glut5)* SLC2A5 AA459707  2.0   1.4  
    Osteopontin* SPP1 R59298  3.0   1.8  
    Interferon γ—induced protein* IFI16 AA126928  2.0   1.0  
    Prepromultimerin  MMRN AA423867  2.1   1.4  
    kiaa0337 gene* KIAA0337 AA236696  2.0   0.7  
Transcription factors/cell cycle     
    v-ets erythroblastosis virus e26 oncogene-like (avian) ERG R01192  2.9   0.9  
    erg2 gene ERG R87572  2.9   0.4  
    cyclin G2* CCNG2 H18981  2.0   0.8  
Cellular component/cytoskeleton     
    Fibronectin (fn precursor)  FN1 W57892  2.1   1.4  
    Dermal fibroblast elastin WDR1 R49766  2.2   0.6  
Other/unknown     
    Williams-Beuren syndrome chromosome region 5 WBSCR5 AF086239  2.1   0.6  
    kiaa 1766 protein  KIAA1766 AI800340  2.1   1.6  
    kiaa0125 gene product KIAA0125 H65343  2.2   0.6  
    Melanoma-associated gene D2S448 R09509  2.0   0.5  
    lim protein slimmer* FHL1 AA134667  2.3   1.1  
    kiaa0581 protein PLCB1 AA011027  2.2   0.8  
    ralgds-like gene  RGL AA013091  2.1   1.9  
    Cysteine and tyrosine-rich 1* CYYR1 AA125921  2.0   0.8  
    Hypothetical protein flj14054 FLJ14054 H68441  2.9   0.8  
    cDNA dkfzp586e1624*  AA042839  2.3   0.8  
    Acyl-protein thioesterase  LYPLA2 R38687  2.3   3.3  
    Hypothetical protein flj10628
 
FLJ10628
 
AA400002
 
2.3
 
0.7
 

Gene

Symbol

Accession no.

Ratio (Log2)

SD
Cell surface receptors/ligands     
    HLA-DR α heavy-chain a class II antigen (MHC)* HLA-DRA H78841  2.5   0.8  
    Peripheral lymph node homing receptor homolog* SELL H00662  3.3   1.3  
    MHC class II dr β* HLA-DRB1,5 H90289  2.0   0.9  
    CD133 antigen PROML1 R40057  3.7   0.8  
    m130 antigen cytoplasmic variant 2* CD163 N73867  3.2   1.7  
    HLA-DP-β 1 gene and HLA-DP-α-1 gene exon 1 HLA-DPB1 AA496472  2.2   0.7  
    Complement component 1, q subcomponent, receptor 1* CIQR1 H28298  2.1   1.6  
    Human platelet endothelial cell adhesion molecule PECAM1 R22412  2.2   0.6  
    Low-affinity IgG receptor CD16 (fcgriii)* FCGR3A N47495  2.7   1.4  
    Toll/IL-1 receptor-like protein 4 (til4)  TLR2 AA004805  2.1   1.6  
    Mannose receptor, c type 1* MRC1 AA043388  2.2   1.0  
    HLA-SB(dp) α gene* HLA-DPA1 H38801  2.0   0.5  
Transporter/signal transduction     
    Multidrug resistance gene 1 (MDR1) ABCB1 AA135957  2.1   0.5  
    Soluble guanylate cyclase small subunit* GUCY1B3 W73155  2.0   1.4  
    Glucose transport-like 5 (glut5)* SLC2A5 AA459707  2.0   1.4  
    Osteopontin* SPP1 R59298  3.0   1.8  
    Interferon γ—induced protein* IFI16 AA126928  2.0   1.0  
    Prepromultimerin  MMRN AA423867  2.1   1.4  
    kiaa0337 gene* KIAA0337 AA236696  2.0   0.7  
Transcription factors/cell cycle     
    v-ets erythroblastosis virus e26 oncogene-like (avian) ERG R01192  2.9   0.9  
    erg2 gene ERG R87572  2.9   0.4  
    cyclin G2* CCNG2 H18981  2.0   0.8  
Cellular component/cytoskeleton     
    Fibronectin (fn precursor)  FN1 W57892  2.1   1.4  
    Dermal fibroblast elastin WDR1 R49766  2.2   0.6  
Other/unknown     
    Williams-Beuren syndrome chromosome region 5 WBSCR5 AF086239  2.1   0.6  
    kiaa 1766 protein  KIAA1766 AI800340  2.1   1.6  
    kiaa0125 gene product KIAA0125 H65343  2.2   0.6  
    Melanoma-associated gene D2S448 R09509  2.0   0.5  
    lim protein slimmer* FHL1 AA134667  2.3   1.1  
    kiaa0581 protein PLCB1 AA011027  2.2   0.8  
    ralgds-like gene  RGL AA013091  2.1   1.9  
    Cysteine and tyrosine-rich 1* CYYR1 AA125921  2.0   0.8  
    Hypothetical protein flj14054 FLJ14054 H68441  2.9   0.8  
    cDNA dkfzp586e1624*  AA042839  2.3   0.8  
    Acyl-protein thioesterase  LYPLA2 R38687  2.3   3.3  
    Hypothetical protein flj10628
 
FLJ10628
 
AA400002
 
2.3
 
0.7
 

The Log2 ratios of SDF/FDF were the average values of 6 hybridizations in 3 experiments. Error estimate is given as SD. Probability of differential gene expression in relation to all high- quality signals was determined with the Student t test. MHC indicates major histocompatibility complex. Accession numbers from GenBank are provided.

*

P < .01.

P < .0001.

P < .001.

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