Table 1. Influence of age on CD4 T-cell... | American Society of Hematology

Table 1.

Influence of age on CD4 T-cell TREC contents in HIV-1-infected subjects at different stages of disease

	HIV-negative				HIV-1-infected
T-cell count and age, y^*	N	TREC contents, mean ± SE	P	N	TREC contents, mean ± SE
More than 500 CD4 T cells
20-39	54	13 206 ± 1245	.016†	56	19 418 ± 2203
40-44	14	5174 ± 945	.015†	11	16 119 ± 3698
45-49	18	7293 ± 1319	.305	18	10 063 ± 2295
50-54	9	5532 ± 1223	.865	7	5133 ± 1899
55-59	7	6921 ± 1608	.029†	7	2252 ± 811
200 to 500 CD4 T cells
20-39	54	13 206 ± 1245	.863	65	13 554 ± 1506
40-44	14	5174 ± 945	.102	17	9089 ± 2088
45-49	18	7293 ± 1319	.682	5	8616 ± 3879
50-54	9	5532 ± 1223	.774	12	6235 ± 1871
55-59	7	6921 ± 1608	.014†	3	1023 ± 989
Fewer than 200 CD4 T cells
20-39	54	13 206 ± 1245	.005†	30	7406 ± 1463
20-29	31	14 696 ± 1573	.060	15	9135 ± 2583
30-39	23	11 199 ± 1977	.047†	15	5676 ± 1331

	HIV-negative				HIV-1-infected
T-cell count and age, y^*	N	TREC contents, mean ± SE	P	N	TREC contents, mean ± SE
More than 500 CD4 T cells
20-39	54	13 206 ± 1245	.016†	56	19 418 ± 2203
40-44	14	5174 ± 945	.015†	11	16 119 ± 3698
45-49	18	7293 ± 1319	.305	18	10 063 ± 2295
50-54	9	5532 ± 1223	.865	7	5133 ± 1899
55-59	7	6921 ± 1608	.029†	7	2252 ± 811
200 to 500 CD4 T cells
20-39	54	13 206 ± 1245	.863	65	13 554 ± 1506
40-44	14	5174 ± 945	.102	17	9089 ± 2088
45-49	18	7293 ± 1319	.682	5	8616 ± 3879
50-54	9	5532 ± 1223	.774	12	6235 ± 1871
55-59	7	6921 ± 1608	.014†	3	1023 ± 989
Fewer than 200 CD4 T cells
20-39	54	13 206 ± 1245	.005†	30	7406 ± 1463
20-29	31	14 696 ± 1573	.060	15	9135 ± 2583
30-39	23	11 199 ± 1977	.047†	15	5676 ± 1331

Values are based on TRECs per 10⁶ CD4 T cells. P values represent t test comparisons between values in the 2 groups.

T-cell counts given are those of HIV-1-infected individuals in that group. Subgroups are stratified by age (in years).

Statistically significant values.