Table 2.

Complications of TM, by age group




0-15 y, % (no. positive/no. tested)

16-24 y, % (no. positive/no. tested)

25 y and older, % (no. positive/no. tested)

Overall, % (no. positive/no. tested)
Infectious complications     
    Hepatitis C exposure, Ab+ or RNA+  5 (6/115)   23 (21/91)   70 (90/128)   35 (117/334)  
    Chronic hepatitis C, Ab+ and RNA+*  100 (3/3)   56 (9/16)   66 (37/56)   65 (49/75)  
    Spontaneous clearance, Ab+ and RNA-  0 (0/3)   43 (6/14)   32 (14/44)   33 (20/61)  
Heart disease requiring medication   0 (0/120)   5 (5/93)   23 (30/128)   10 (35/341)  
Cirrhosis by biopsy   4 (3/70)   10 (6/62)   15 (15/100)   10 (24/232)  
Liver failure/cirrhosis by clinical findings   0 (0/119)   5 (5/93)   6 (8/125)   4 (13/337)  
Endocrine disorders     
    Thyroid disease   0   8   17   9  
    Hypoparathyroidism   0   1   9   4  
    Diabetes mellitus   0   9   21   10  
    Hypogonadism requiring medications   0   41   62   35  
    More than 0 endocrinopathies   0   45   67   38  
    More than 1 endocrinopathy   0   10   27   13  
    More than 2 endocrinopathies   0   3   12   6  
    More than 3 endocrinopathies
 
0
 
0
 
2
 
1
 



0-15 y, % (no. positive/no. tested)

16-24 y, % (no. positive/no. tested)

25 y and older, % (no. positive/no. tested)

Overall, % (no. positive/no. tested)
Infectious complications     
    Hepatitis C exposure, Ab+ or RNA+  5 (6/115)   23 (21/91)   70 (90/128)   35 (117/334)  
    Chronic hepatitis C, Ab+ and RNA+*  100 (3/3)   56 (9/16)   66 (37/56)   65 (49/75)  
    Spontaneous clearance, Ab+ and RNA-  0 (0/3)   43 (6/14)   32 (14/44)   33 (20/61)  
Heart disease requiring medication   0 (0/120)   5 (5/93)   23 (30/128)   10 (35/341)  
Cirrhosis by biopsy   4 (3/70)   10 (6/62)   15 (15/100)   10 (24/232)  
Liver failure/cirrhosis by clinical findings   0 (0/119)   5 (5/93)   6 (8/125)   4 (13/337)  
Endocrine disorders     
    Thyroid disease   0   8   17   9  
    Hypoparathyroidism   0   1   9   4  
    Diabetes mellitus   0   9   21   10  
    Hypogonadism requiring medications   0   41   62   35  
    More than 0 endocrinopathies   0   45   67   38  
    More than 1 endocrinopathy   0   10   27   13  
    More than 2 endocrinopathies   0   3   12   6  
    More than 3 endocrinopathies
 
0
 
0
 
2
 
1
 

In this cross-sectional methodology, not every patient is screened for every test. Evidence of hepatitis C by liver biopsy was not queried by the database.

For the endocrine disorders, the numbers of patients in each age group and overall were 120, 93, 129, and 342, respectively.

*

These results are of the patients (n = 75) with a positive test for anti-HCV antibodies and a concurrent or subsequent HCV RNA assay.

These results are of the patients (n = 61) with a positive test for anti-HCV antibodies and a concurrent or subsequent HCV RNA assay who have never been treated for hepatitis C.

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