Dosimetry (cGy/mCi) predicted from 111In data
. | 90Y cGy/mCi . | . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients . | Whole body . | Marrow . | Liver . | Spleen . | Kidney . | Bladder wall . | Tumor(s) . | ||||||
| Cohort A | |||||||||||||
| 1 | ND | ND | ND | ND | ND | ND | ND | ||||||
| 2 | 0.68 | 0.27 | 0.89 | 1.34 | 3.21 | 4.28 | ND | ||||||
| 3 | 0.59 | 0.36 | 1.32 | 1.92 | 6.08 | 4.47 | 45, 56 | ||||||
| Mean ± SD | 0.6 ± 0.04 | 0.3 ± 0.04 | 1.1 ± 0.2 | 1.6 ± 0.3 | 4.6 ± 1.4 | 4.4 ± 0.09 | NA | ||||||
| Cohort B | |||||||||||||
| 4 | 0.30 | 0.17 | 1.28 | 2.33 | 6.7 | 5.02 | 51 | ||||||
| 5 | 0.75 | 0.16 | 1.89 | 6.97 | 5.21 | 4.11 | 8, 2 | ||||||
| 6 | 0.49 | 0.08 | 2.14 | 3.01 | 11.2 | 9.67 | 13, 18, 20 | ||||||
| 8 | 0.36 | 0.06 | 1.15 | 0.98 | 5.5 | 10.45 | 19, 45 | ||||||
| Mean ± SD | 0.5 ± 0.09 | 0.1 ± 0.02 | 1.6 ± 0.2 | 3.3 ± 1.3 | 7.2 ± 1.4 | 7.3 ± 1.6 | NA | ||||||
| Cohort C | |||||||||||||
| 9 | 0.45 | 0.70 | 1.06 | 5.15 | 15.0 | 9.45 | 8, 30, 27 | ||||||
| 10 | 0.71 | 0.26 | 1.05 | 3.1 | 7.7 | 7.63 | 9 | ||||||
| 11 | 0.54 | 0.20 | 2.13 | 4.5 | 16.6 | 10.1 | ND | ||||||
| 12 | 0.71 | 0.23 | 0.97 | 4.82 | 5.31 | 7.99 | ND | ||||||
| Mean ± SD | 0.6 ± 0.06 | 0.3 ± 0.11 | 1.3 ± 0.3 | 4.4 ± 0.5 | 11 ± 3 | 8.8 ± 0.58 | NA | ||||||
| Cohort D | |||||||||||||
| 13 | 0.49 | 0.21 | 1.26 | 13.5 | 8.13 | 8.14 | 69, 34 | ||||||
| 14 | 0.59 | 0.17 | 1.15 | 3.87 | 9.73 | 7.75 | 13, 32, 20 | ||||||
| 15 | 0.46 | 0.16 | 0.69 | 0.69 | 6.28 | 7.34 | 6 | ||||||
| Mean ± SD | 0.5 ± 0.03 | 0.2 ± 0.01 | 1 ± 0.2 | 6 ± 3.9 | 8 ± 1 | 7.7 ± 0.23 | NA | ||||||
| Overall mean ± SD | 0.6 ± 0.05 | 0.2 ± 0.04 | 1.2 ± 0.2 | 3.8 ± 1.2 | 7.7 ± 1.7 | 7 ± 0.63 | 26 ± 4 | ||||||
. | 90Y cGy/mCi . | . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients . | Whole body . | Marrow . | Liver . | Spleen . | Kidney . | Bladder wall . | Tumor(s) . | ||||||
| Cohort A | |||||||||||||
| 1 | ND | ND | ND | ND | ND | ND | ND | ||||||
| 2 | 0.68 | 0.27 | 0.89 | 1.34 | 3.21 | 4.28 | ND | ||||||
| 3 | 0.59 | 0.36 | 1.32 | 1.92 | 6.08 | 4.47 | 45, 56 | ||||||
| Mean ± SD | 0.6 ± 0.04 | 0.3 ± 0.04 | 1.1 ± 0.2 | 1.6 ± 0.3 | 4.6 ± 1.4 | 4.4 ± 0.09 | NA | ||||||
| Cohort B | |||||||||||||
| 4 | 0.30 | 0.17 | 1.28 | 2.33 | 6.7 | 5.02 | 51 | ||||||
| 5 | 0.75 | 0.16 | 1.89 | 6.97 | 5.21 | 4.11 | 8, 2 | ||||||
| 6 | 0.49 | 0.08 | 2.14 | 3.01 | 11.2 | 9.67 | 13, 18, 20 | ||||||
| 8 | 0.36 | 0.06 | 1.15 | 0.98 | 5.5 | 10.45 | 19, 45 | ||||||
| Mean ± SD | 0.5 ± 0.09 | 0.1 ± 0.02 | 1.6 ± 0.2 | 3.3 ± 1.3 | 7.2 ± 1.4 | 7.3 ± 1.6 | NA | ||||||
| Cohort C | |||||||||||||
| 9 | 0.45 | 0.70 | 1.06 | 5.15 | 15.0 | 9.45 | 8, 30, 27 | ||||||
| 10 | 0.71 | 0.26 | 1.05 | 3.1 | 7.7 | 7.63 | 9 | ||||||
| 11 | 0.54 | 0.20 | 2.13 | 4.5 | 16.6 | 10.1 | ND | ||||||
| 12 | 0.71 | 0.23 | 0.97 | 4.82 | 5.31 | 7.99 | ND | ||||||
| Mean ± SD | 0.6 ± 0.06 | 0.3 ± 0.11 | 1.3 ± 0.3 | 4.4 ± 0.5 | 11 ± 3 | 8.8 ± 0.58 | NA | ||||||
| Cohort D | |||||||||||||
| 13 | 0.49 | 0.21 | 1.26 | 13.5 | 8.13 | 8.14 | 69, 34 | ||||||
| 14 | 0.59 | 0.17 | 1.15 | 3.87 | 9.73 | 7.75 | 13, 32, 20 | ||||||
| 15 | 0.46 | 0.16 | 0.69 | 0.69 | 6.28 | 7.34 | 6 | ||||||
| Mean ± SD | 0.5 ± 0.03 | 0.2 ± 0.01 | 1 ± 0.2 | 6 ± 3.9 | 8 ± 1 | 7.7 ± 0.23 | NA | ||||||
| Overall mean ± SD | 0.6 ± 0.05 | 0.2 ± 0.04 | 1.2 ± 0.2 | 3.8 ± 1.2 | 7.7 ± 1.7 | 7 ± 0.63 | 26 ± 4 | ||||||
ND indicates not determined; NA, not applicable.