Reactive causes of eosinophilia
Allergic/hypersensitivity diseases |
| Asthma, rhinitis, drug reactions, allergic bronchopulmonary aspergillosis, allergic gastroenteritis |
| Infections |
| Parasitic (strongyloidiasis, Toxocara canis, Trichinella spiralis, visceral larva migrans, filariasis, schistosomiasis, Ancylostoma duodenale, Fasciola hepatica, Echinococcus, Toxoplasma, other parasitic diseases) |
| Bacterial/mycobacterial |
| Fungal (coccidioidomycosis, cryptococcus) |
| Viral (HIV, herpes simplex virus [HSV], human T-cell leukemia virus type 2 [HTLV-2]) |
| Rickettsial |
| Connective tissue diseases |
| Churg-Strauss syndrome, Wegener granulomatosis, rheumatoid arthritis, polyarteritis nodosa, systemic lupus erythematosus, scleroderma, eosinophilic fasciitis/myositis |
| Pulmonary diseases |
| Bronchiectasis, cystic fibrosis, Loeffler syndrome, eosinophilic granuloma of the lung |
| Cardiac diseases |
| Tropical endocardial fibrosis, eosinophilic endomyocardial fibrosis or myocarditis |
| Skin diseases |
| Atopic dermatitis, urticaria, eczema, bullous pemphigoid, dermatitis herpetiformis, episodic angioedema with eosinophilia (Gleich syndrome) |
| Gastrointestinal diseases |
| Eosinophilic gastroenteritis, celiac disease |
| Malignancies |
| Hodgkin and non-Hodgkin lymphoma, acute lymphoblastic leukemia, Langerhans cell histiocytosis, angiolymphoid hyperplasia with eosinophilia (Kimura disease), angioimmunoblastic lymphadenopathy, solid tumors (eg, renal, lung, breast, vascular neoplasms, female genital tract cancers) |
| Immune system diseases/abnormalities |
| Wiskott-Aldrich syndrome, hyper-IgE (Job) syndrome, hyper-IgM syndrome, IgA deficiency |
| Metabolic abnormalities |
| Adrenal insufficiency |
| Other |
| IL-2 therapy, L-tryptophan ingestion, toxic oil syndrome, renal graft rejection |
Allergic/hypersensitivity diseases |
| Asthma, rhinitis, drug reactions, allergic bronchopulmonary aspergillosis, allergic gastroenteritis |
| Infections |
| Parasitic (strongyloidiasis, Toxocara canis, Trichinella spiralis, visceral larva migrans, filariasis, schistosomiasis, Ancylostoma duodenale, Fasciola hepatica, Echinococcus, Toxoplasma, other parasitic diseases) |
| Bacterial/mycobacterial |
| Fungal (coccidioidomycosis, cryptococcus) |
| Viral (HIV, herpes simplex virus [HSV], human T-cell leukemia virus type 2 [HTLV-2]) |
| Rickettsial |
| Connective tissue diseases |
| Churg-Strauss syndrome, Wegener granulomatosis, rheumatoid arthritis, polyarteritis nodosa, systemic lupus erythematosus, scleroderma, eosinophilic fasciitis/myositis |
| Pulmonary diseases |
| Bronchiectasis, cystic fibrosis, Loeffler syndrome, eosinophilic granuloma of the lung |
| Cardiac diseases |
| Tropical endocardial fibrosis, eosinophilic endomyocardial fibrosis or myocarditis |
| Skin diseases |
| Atopic dermatitis, urticaria, eczema, bullous pemphigoid, dermatitis herpetiformis, episodic angioedema with eosinophilia (Gleich syndrome) |
| Gastrointestinal diseases |
| Eosinophilic gastroenteritis, celiac disease |
| Malignancies |
| Hodgkin and non-Hodgkin lymphoma, acute lymphoblastic leukemia, Langerhans cell histiocytosis, angiolymphoid hyperplasia with eosinophilia (Kimura disease), angioimmunoblastic lymphadenopathy, solid tumors (eg, renal, lung, breast, vascular neoplasms, female genital tract cancers) |
| Immune system diseases/abnormalities |
| Wiskott-Aldrich syndrome, hyper-IgE (Job) syndrome, hyper-IgM syndrome, IgA deficiency |
| Metabolic abnormalities |
| Adrenal insufficiency |
| Other |
| IL-2 therapy, L-tryptophan ingestion, toxic oil syndrome, renal graft rejection |