The effect of rapamycin and dexamethasone on apoptosis in 2 MM cell lines
Treatment
.
Karpas 707
.
U-1958
.
Control
9 ± 4
21 ± 11
Rap
15 ± 6
37 ± 12
Dex
47 ± 4
32 ± 7
Rap + Dex
75 ± 3
66 ± 10
Treatment
.
Karpas 707
.
U-1958
.
Control
9 ± 4
21 ± 11
Rap
15 ± 6
37 ± 12
Dex
47 ± 4
32 ± 7
Rap + Dex
75 ± 3
66 ± 10
Karpas 707 and U-1958 cells were treated with rapamycin (Rap) and/or dexamethasone (Dex) for 48 hours, then apoptosis was analyzed using the TUNEL assay. Three independent experiments per cell line were performed, and results are presented as mean percentage apoptotic cells ± SD where n = 3.