Association between potential productive rearrangement and VH segment utilization
Gene family . | Potential productive (%) . | Potential Nonproductive (%) . | Percentage of productive within VH gene family . |
---|---|---|---|
VH1 | 4 (5) | 58 (19) | 6 (4 of 62) |
VH2 | 5 (6) | 17 (6) | 23 (5 of 22) |
VH3 | 40 (51) | 152 (50) | 21 (40 of 192) |
VH4 | 22 (28) | 38 (13) | 37 (22 of 60) |
VH5 | 3 (4) | 7 (2) | 30 (3 of 10) |
VH6 | 5 (6) | 30 (10) | 14 (5 of 35) |
Total | 79 (21) | 302 (79) |
Gene family . | Potential productive (%) . | Potential Nonproductive (%) . | Percentage of productive within VH gene family . |
---|---|---|---|
VH1 | 4 (5) | 58 (19) | 6 (4 of 62) |
VH2 | 5 (6) | 17 (6) | 23 (5 of 22) |
VH3 | 40 (51) | 152 (50) | 21 (40 of 192) |
VH4 | 22 (28) | 38 (13) | 37 (22 of 60) |
VH5 | 3 (4) | 7 (2) | 30 (3 of 10) |
VH6 | 5 (6) | 30 (10) | 14 (5 of 35) |
Total | 79 (21) | 302 (79) |
Association between VH family usage and potential productive rearrangements (P = .002 by the χ2 test, and P = .001 by the Fisher exact test).