Table 3. Demographic and hematologic... | American Society of Hematology

Table 3.

Demographic and hematologic profile by ELA2 genotype

	SCN group					CN group
	NN	NM	P	NN	NM	P
Peripheral blood
No. patients	35	19	—	15	12	—
Mean no. of analyzed blood samples	16	20	—	13	21	—
Neutrophils, × 10⁹/L^*	0.38	0.13	.002	0.84	0.64	NS
Monocytes, × 10⁹/L^*	0.64	1.33	.01	0.36	0.69	.007
Bone marrow cytology, normal range^*				NA†	NA	—
No. patients.	19	19	—
Myeloblasts, 0.3-2.4, %	2.7	3.5	NS
Promyelocytes-myelocytes, 12-25, %	13.2	4.9	.002
Metamyelocytes-neutrophils, 33-48, %	13.3	3.1	.002

	SCN group					CN group
	NN	NM	P	NN	NM	P
Peripheral blood
No. patients	35	19	—	15	12	—
Mean no. of analyzed blood samples	16	20	—	13	21	—
Neutrophils, × 10⁹/L^*	0.38	0.13	.002	0.84	0.64	NS
Monocytes, × 10⁹/L^*	0.64	1.33	.01	0.36	0.69	.007
Bone marrow cytology, normal range^*				NA†	NA	—
No. patients.	19	19	—
Myeloblasts, 0.3-2.4, %	2.7	3.5	NS
Promyelocytes-myelocytes, 12-25, %	13.2	4.9	.002
Metamyelocytes-neutrophils, 33-48, %	13.3	3.1	.002

NS indicates not significant; NA, not analyzed; NN genotype, patient with no ELA2 mutation; NM genotype, patient with a heterozygous ELA2 mutation; and —, not applicable.

Measurements are expressed as the median of counts

†

No analysis of bone marrow data in patients with CN because of variable periods of neutropenia

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