Table 2. Numbers of erythroblasts at... | American Society of Hematology

Table 2.

Numbers of erythroblasts at different maturation stages in naive or P chabaudi AS–infected mice with or without EPO treatment

	N	N + EPO*	I	I + EPO*
I: CD71^highTER119^low	0.20 ± 0.07^a	6.93 ± 0.13^b	1.97 ± 0.58^c	5.79 ± 0.60^d
II: CD71^highTER119^high	0.42 ± 0.17^a	11.27 ± 0.51^b	1.23 ± 0.33^a,c	2.05 ± 0.35^c
III: CD71^low-medTER119^high	2.43 ± 0.59^a	57.60 ± 1.39^b	4.43 ± 1.14^a	10.93 ± 1.57^c
IV: CD71^medTER119^-	1.51 ± 0.30^a	4.99 ± 0.09^b	19.61 ± 2.44^c	33.11 ± 2.22^d

	N	N + EPO*	I	I + EPO*
I: CD71^highTER119^low	0.20 ± 0.07^a	6.93 ± 0.13^b	1.97 ± 0.58^c	5.79 ± 0.60^d
II: CD71^highTER119^high	0.42 ± 0.17^a	11.27 ± 0.51^b	1.23 ± 0.33^a,c	2.05 ± 0.35^c
III: CD71^low-medTER119^high	2.43 ± 0.59^a	57.60 ± 1.39^b	4.43 ± 1.14^a	10.93 ± 1.57^c
IV: CD71^medTER119^-	1.51 ± 0.30^a	4.99 ± 0.09^b	19.61 ± 2.44^c	33.11 ± 2.22^d

Erythroblasts were identified by double staining with FITC-conjugated anti-CD71 and PE-conjugated anti-TER119 antibodies. Region I: proerythroblasts. Region II: basophilic erythroblasts. Region III: polychromatic and orthochromatic erythroblasts. Region IV: nonerythroblast population expressing CD71. Data are means ± SEM × 10⁶ cells per spleen for 3 to 5 mice per group. When 2 sets of data are labeled with superscripts of lowercase letters, it indicates that these 2 sets of data are statisitcally different (P < .05). Similar results were obtained in 2 independent experiments.

Abbreviations are explained in the footnotes to Table 1.

Naive or infected A/J mice were treated with 10 units of rmEPO per day for 3 consecutive days. Mice were humanely killed 1 day following the completion of the treatment, and spleen parameters were assessed.

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