Table 1. Proteins released from... | American Society of Hematology

Table 1.

Proteins released from thrombin-activated platelets identified by MALDI-TOF MS

Spot no.	Protein identity	Accession no.	Molecular weight, M_r	Isoelectric point, pl	Sequence coverage, %	MOWSE score
1	Apo A1 fragment	CAA00975	28 061	5.27	59	232
2	Apo A1 fragment	CAA00975	28 061	5.27	46	125
3	14-3-3 protein ζ/δ	1QIBA	26 297	4.99	38	116
4	TMP4-ALK fusion oncoprotein type 2	Q9HBZ0	27 570	4.77	29	102
5	Haptoglobin	AAC27432	38 722	6.14	25	91
6	Haptoglobin	AAC27432	38 722	6.14	36	151
7	Haptoglobin	AAC27432	38 722	6.14	30	137
8	Haptoglobin	AAC27432	38 722	6.14	36	140
9	Actin	CAA27396	39 446	5.78	54	158
10	Osteonectin	O08953	35 129	4.81	37	127
11	Osteonectin	O08953	35 129	4.81	37	119
12	Thrombospondin	CAA32889	133 261	4.71	15	111
13	α₁-antitrypsin	CAA00206	44 291	5.36	21	120
14	α_j-antitrypsin	CAA00206	44 291	5.36	21	109
15	α₁-antitrypsin	CAA00206	44 291	5.36	21	120
16	Serum albumin	CAA00298	68 588	5.67	30	194
17	Serum albumin	1AO6A	676 090	5.63	27	161
18	Serum albumin	CAA00298	68 588	5.67	27	159
19	Albumin	CAA01216	68 425	5.67	29	154
20	Serum albumin	1AO6A	67 690	5.63	25	164
21	Serum albumin	1AO6A	67 690	5.63	17	90
22	Albumin	AA64922	53 416	5.69	33	150

Spot no.	Protein identity	Accession no.	Molecular weight, M_r	Isoelectric point, pl	Sequence coverage, %	MOWSE score
1	Apo A1 fragment	CAA00975	28 061	5.27	59	232
2	Apo A1 fragment	CAA00975	28 061	5.27	46	125
3	14-3-3 protein ζ/δ	1QIBA	26 297	4.99	38	116
4	TMP4-ALK fusion oncoprotein type 2	Q9HBZ0	27 570	4.77	29	102
5	Haptoglobin	AAC27432	38 722	6.14	25	91
6	Haptoglobin	AAC27432	38 722	6.14	36	151
7	Haptoglobin	AAC27432	38 722	6.14	30	137
8	Haptoglobin	AAC27432	38 722	6.14	36	140
9	Actin	CAA27396	39 446	5.78	54	158
10	Osteonectin	O08953	35 129	4.81	37	127
11	Osteonectin	O08953	35 129	4.81	37	119
12	Thrombospondin	CAA32889	133 261	4.71	15	111
13	α₁-antitrypsin	CAA00206	44 291	5.36	21	120
14	α_j-antitrypsin	CAA00206	44 291	5.36	21	109
15	α₁-antitrypsin	CAA00206	44 291	5.36	21	120
16	Serum albumin	CAA00298	68 588	5.67	30	194
17	Serum albumin	1AO6A	676 090	5.63	27	161
18	Serum albumin	CAA00298	68 588	5.67	27	159
19	Albumin	CAA01216	68 425	5.67	29	154
20	Serum albumin	1AO6A	67 690	5.63	25	164
21	Serum albumin	1AO6A	67 690	5.63	17	90
22	Albumin	AA64922	53 416	5.69	33	150

Protein identifications were generated from the MASCOT database. The validity of the matches was quantified using MOWSE probability score. The percentage of the protein sequence matched by the generated peptides (the sequence coverage) was also documented.

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